中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid

文献类型:期刊论文

作者Yan, Shifeng1; Yin, Jingbo1; Cui, Lei2; Yang, Yan1; Chen, Xuesi3
刊名COLLOIDS AND SURFACES B-BIOINTERFACES
出版日期2011-08-01
卷号86期号:1页码:218-224
关键词Poly(L-lactic Acid) Scaffold Apatite Nanocomposites
ISSN号0927-7765
DOI10.1016/j.colsurfb.2011.04.004
英文摘要Bioactive PLLA/surface-grafted silica (g-SiO(2)) nanocomposite scaffolds were fabricated by solid-liquid phase separation method. And solid PLLA/g-SiO(2) nanocomposite films were prepared by solution casting method. A series of parallel tube-like morphology and internal ladder-like structure of PLLA/g-SiO(2) nanocomposite scaffolds were observed by SEM. The formation of bone-like apatite in the simulated body fluid (SBF) was characterized by XRD, IR, SEM, EDS and weight measurement. The silica incorporation favors the formation of apatite. The growth of apatite with immersion time is found on the surfaces of both the PLLA/g-SiO(2) nanocomposite scaffolds and the films. The potential mechanism is that silanol groups of g-SiO(2) in the nanocomposites serve as nucleation sites for the formation of bone-like apatite crystals. (C) 2011 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000291458100031
出版者ELSEVIER SCIENCE BV
源URL[http://ir.iccas.ac.cn/handle/121111/73685]  
专题中国科学院化学研究所
通讯作者Yin, Jingbo
作者单位1.Shanghai Univ, Sch Mat Sci & Engn, Dept Polymer Mat, Shanghai 201800, Peoples R China
2.Natl Tissue Engn Ctr China, Shanghai 200233, Peoples R China
3.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
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Yan, Shifeng,Yin, Jingbo,Cui, Lei,et al. Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2011,86(1):218-224.
APA Yan, Shifeng,Yin, Jingbo,Cui, Lei,Yang, Yan,&Chen, Xuesi.(2011).Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid.COLLOIDS AND SURFACES B-BIOINTERFACES,86(1),218-224.
MLA Yan, Shifeng,et al."Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid".COLLOIDS AND SURFACES B-BIOINTERFACES 86.1(2011):218-224.

入库方式: OAI收割

来源:化学研究所

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