Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid
文献类型:期刊论文
作者 | Yan, Shifeng1; Yin, Jingbo1; Cui, Lei2; Yang, Yan1; Chen, Xuesi3 |
刊名 | COLLOIDS AND SURFACES B-BIOINTERFACES
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出版日期 | 2011-08-01 |
卷号 | 86期号:1页码:218-224 |
关键词 | Poly(L-lactic Acid) Scaffold Apatite Nanocomposites |
ISSN号 | 0927-7765 |
DOI | 10.1016/j.colsurfb.2011.04.004 |
英文摘要 | Bioactive PLLA/surface-grafted silica (g-SiO(2)) nanocomposite scaffolds were fabricated by solid-liquid phase separation method. And solid PLLA/g-SiO(2) nanocomposite films were prepared by solution casting method. A series of parallel tube-like morphology and internal ladder-like structure of PLLA/g-SiO(2) nanocomposite scaffolds were observed by SEM. The formation of bone-like apatite in the simulated body fluid (SBF) was characterized by XRD, IR, SEM, EDS and weight measurement. The silica incorporation favors the formation of apatite. The growth of apatite with immersion time is found on the surfaces of both the PLLA/g-SiO(2) nanocomposite scaffolds and the films. The potential mechanism is that silanol groups of g-SiO(2) in the nanocomposites serve as nucleation sites for the formation of bone-like apatite crystals. (C) 2011 Elsevier B.V. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000291458100031 |
出版者 | ELSEVIER SCIENCE BV |
源URL | [http://ir.iccas.ac.cn/handle/121111/73685] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Yin, Jingbo |
作者单位 | 1.Shanghai Univ, Sch Mat Sci & Engn, Dept Polymer Mat, Shanghai 201800, Peoples R China 2.Natl Tissue Engn Ctr China, Shanghai 200233, Peoples R China 3.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China |
推荐引用方式 GB/T 7714 | Yan, Shifeng,Yin, Jingbo,Cui, Lei,et al. Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2011,86(1):218-224. |
APA | Yan, Shifeng,Yin, Jingbo,Cui, Lei,Yang, Yan,&Chen, Xuesi.(2011).Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid.COLLOIDS AND SURFACES B-BIOINTERFACES,86(1),218-224. |
MLA | Yan, Shifeng,et al."Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid".COLLOIDS AND SURFACES B-BIOINTERFACES 86.1(2011):218-224. |
入库方式: OAI收割
来源:化学研究所
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