The fabrication and characterization of poly(lactic acid) scaffolds for tissue engineering by improved solid-liquid phase separation
文献类型:期刊论文
作者 | Tu, CF; Cai, Q; Yang, J; Wan, YQ; Bei, JZ; Wang, S |
刊名 | POLYMERS FOR ADVANCED TECHNOLOGIES
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出版日期 | 2003-08-01 |
卷号 | 14期号:8页码:565-573 |
关键词 | Phase Separation Microstructure Polyesters Scaffold Cell Culture |
ISSN号 | 1042-7147 |
DOI | 10.1002/pat.370 |
英文摘要 | In this article a new technique was developed to fabricate scaffolds with a unique microstructure by solid-liquid separation in combination with particulate-leaching. Firstly, the effects of polymer concentration, quenching temperature on the porous morphology and the mechanical property of obtained scaffolds during solid-liquid separation have been investigated. Then, salt granules as porogen were introduced into the solid-liquid phase separation to produce the unique pore structure of the scaffold. The pore diameter of the scaffold could be controlled with the particulate size and the wall of pores possessed special microstructure, which enhanced the pore interconnectivity. The cell culture results confirmed that a good interconnectivity of the scaffold prepared by the improved solid-liquid separation was useful for nutrition transportation and cell proliferation. Copyright (C) 2003 John Wiley Sons, Ltd. |
语种 | 英语 |
WOS记录号 | WOS:000184725100006 |
出版者 | JOHN WILEY & SONS LTD |
源URL | [http://ir.iccas.ac.cn/handle/121111/79661] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Wang, S |
作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, PCCL, Beijing 100080, Peoples R China |
推荐引用方式 GB/T 7714 | Tu, CF,Cai, Q,Yang, J,et al. The fabrication and characterization of poly(lactic acid) scaffolds for tissue engineering by improved solid-liquid phase separation[J]. POLYMERS FOR ADVANCED TECHNOLOGIES,2003,14(8):565-573. |
APA | Tu, CF,Cai, Q,Yang, J,Wan, YQ,Bei, JZ,&Wang, S.(2003).The fabrication and characterization of poly(lactic acid) scaffolds for tissue engineering by improved solid-liquid phase separation.POLYMERS FOR ADVANCED TECHNOLOGIES,14(8),565-573. |
MLA | Tu, CF,et al."The fabrication and characterization of poly(lactic acid) scaffolds for tissue engineering by improved solid-liquid phase separation".POLYMERS FOR ADVANCED TECHNOLOGIES 14.8(2003):565-573. |
入库方式: OAI收割
来源:化学研究所
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