Adaptive hormetic response of pre-exposure of mouse brain with low-dose C-12(6+) ion or Co-60 gamma-ray on growth hormone (GH) and body weight induced by subsequent high-dose irradiation
文献类型：会议论文
| 作者 | Zhang, Hong ; Xie, Yi; Zhou, Qingming; Liu, Bing; Li, Wenjian; Li, Xiaoda; Duan, Xin; Yuan, Zhigang; Zhou, Guangming; Min, Fengling
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| 出版日期 | 2006 |
| 关键词 | C-12(6+) heavy ion Co-60 gamma-ray low-dose pre-exposure mouse pituitary growth hormone (GH) adaptive hormetic response |
| 卷号 | 38 |
| 期号 | 6 |
| DOI | 10.1016/j.asr.2006.03.030 |
| 页码 | 1148-+ |
| 英文摘要 | The brain of the Kun-Ming strain mice were irradiated with 0.05 Gy of C-12(6+) ion or (CO)-C-60 gamma-ray as the pre-exposure dose, and were then irradiated with 2 Gy of C-12(6+) ion or Co-60 gamma-ray as challenging irradiation dose at 4 It after per-exposure. Body weight and serum growth hormone (GH) concentration were measured at 35th day after irradiation. The results showed that irradiation of mouse brain with 2 Gy of C-12(6+) ion or 60CO gamma-ray significantly diminished mouse body weight and level of serum GH. The relative biological effectiveness values of a 2 Gy dose of C-12(6+) ion calculated with respect to 60CO gamma-ray were 1.47 and 1.34 for body weight and serum GH concentration, respectively. Pre-exposure with a low-dose (0.05 Gy) of C-12(6+) ion or 60CO gamma-ray significantly alleviated reductions of mouse body weight and level of serum GH induced by a subsequent high-dose (2 Gy) irradiation. The data suggested that low-dose ionizing irradiation can induce adaptive hormetic responses to the harmful effects of pituitary by subsequent high-dose exposure. (c) 2006 COSPAR. Published by Elsevier Ltd. All rights reserved. |
| 会议录 | SPACE LIFE SCIENCES
 |
| 会议录出版者 | ELSEVIER SCIENCE LTD |
| 会议录出版地 | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD 0X5 1GB, OXON, ENGLAND |
| 语种 | 英语 |
| WOS研究方向 | Engineering ; Astronomy & Astrophysics ; Life Sciences & Biomedicine - Other Topics ; Geology ; Meteorology & Atmospheric Sciences |
| WOS记录号 | WOS:000245034100019 |
| 源URL | [http://119.78.100.186/handle/113462/58101]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Zhang, Hong |
| 作者单位 | Chinese Acad Sci, Dept Med Phys, Inst Modern Phys, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hong,Xie, Yi,Zhou, Qingming,et al. Adaptive hormetic response of pre-exposure of mouse brain with low-dose C-12(6+) ion or Co-60 gamma-ray on growth hormone (GH) and body weight induced by subsequent high-dose irradiation[C]. 见:. |
入库方式： OAI收割
来源：近代物理研究所
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