Nephrotoxic effects from chronic toxic cyanobacterial blooms in fishes with different trophic levels in a large Chinese lake
文献类型：期刊论文
| 作者 | Qiu, Tong1,2; Xie, Ping1; Li, Li3; Guo, Longgen1; Zhang, Dawen1; Zhou, Qiong1 |
| 刊名 | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
 |
| 出版日期 | 2012-03-01 |
| 卷号 | 33期号:2页码:252-261 |
| 关键词 | Toxic cyanobacterial blooms Fish Trophic level Kidney Antioxidants system Ultrastructure |
| ISSN号 | 1382-6689 |
| 通讯作者 | Xie, P (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China. |
| 中文摘要 | Physiological and biochemical responses in kidneys of fishes with different trophic levels to toxic cyanobacterial blooms were studied. We sampled four fishes: the phytoplanktivorous Hypophthalmichthys molitrix and Aristichthys nobilis, the omnivorous Carassius auratus, and the carnivorous Culter ilishaeformis. Alterations of the antioxidant (GSH) and the major antioxidant enzymes (CAT, SOD, GPx, GST) were monitored monthly. Catalase and glutathione S-transferase were significantly higher during blooms than before and after blooms. All fishes showed ultrastructural alterations during blooms, which mainly are inosculation of foot processes in epithelial cell of glomeruli and mitochondria swelling in the proximal tubules. The results suggested that kidney impairment from chronic exposure of toxic cyanobacterial blooms might be the first step, and then followed by hepatic failure. Compared with livers in terms of physiological status, the weaker antioxidant ability of kidney made it more susceptible to chronic MCs exposure, besides its effective accumulation of MC metabolites. (C) 2011 Elsevier B.V. All rights reserved. |
| 英文摘要 | Physiological and biochemical responses in kidneys of fishes with different trophic levels to toxic cyanobacterial blooms were studied. We sampled four fishes: the phytoplanktivorous Hypophthalmichthys molitrix and Aristichthys nobilis, the omnivorous Carassius auratus, and the carnivorous Culter ilishaeformis. Alterations of the antioxidant (GSH) and the major antioxidant enzymes (CAT, SOD, GPx, GST) were monitored monthly. Catalase and glutathione S-transferase were significantly higher during blooms than before and after blooms. All fishes showed ultrastructural alterations during blooms, which mainly are inosculation of foot processes in epithelial cell of glomeruli and mitochondria swelling in the proximal tubules. The results suggested that kidney impairment from chronic exposure of toxic cyanobacterial blooms might be the first step, and then followed by hepatic failure. Compared with livers in terms of physiological status, the weaker antioxidant ability of kidney made it more susceptible to chronic MCs exposure, besides its effective accumulation of MC metabolites. (C) 2011 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Environmental Sciences ; Pharmacology & Pharmacy ; Toxicology |
| 研究领域[WOS] | Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology |
| 关键词[WOS] | FRESH-WATER FISH ; OXIDATIVE STRESS ; IN-SITU ; BIOCHEMICAL RESPONSES ; MICROCYSTIS BLOOMS ; OREOCHROMIS SP. ; LR ; BIOACCUMULATION ; HEPATOPANCREAS ; HEPATOTOXINS |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China[30530170] |
| 语种 | 英语 |
| WOS记录号 | WOS:000301475000016 |
| 公开日期 | 2012-09-25 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/16885]  |
| 专题 | 水生生物研究所_淡水生态学研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China 2.Wuhan Univ Technol, Biomed Mat & Engn Ctr, Wuhan 430070, Peoples R China 3.Huazhong Agr Univ, Coll Fisheries, Wuhan 430070, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiu, Tong,Xie, Ping,Li, Li,et al. Nephrotoxic effects from chronic toxic cyanobacterial blooms in fishes with different trophic levels in a large Chinese lake[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2012,33(2):252-261. |
| APA | Qiu, Tong,Xie, Ping,Li, Li,Guo, Longgen,Zhang, Dawen,&Zhou, Qiong.(2012).Nephrotoxic effects from chronic toxic cyanobacterial blooms in fishes with different trophic levels in a large Chinese lake.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,33(2),252-261. |
| MLA | Qiu, Tong,et al."Nephrotoxic effects from chronic toxic cyanobacterial blooms in fishes with different trophic levels in a large Chinese lake".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 33.2(2012):252-261. |
入库方式： OAI收割
来源：水生生物研究所
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