A microarray image gridding method based on image projection difference sequences analysis and local extrema searching
文献类型：会议论文
| 作者 | Liu J(刘军); Feng YJ(冯艳君); Liu WJ(刘伟军) ; Wang TR(王天然)
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| 出版日期 | 2012 |
| 会议名称 | 10th World Congress on Intelligent Control and Automation, WCICA 2012 |
| 会议日期 | July 6-8, 2012 |
| 会议地点 | Beijing, China |
| 关键词 | Genes Intelligent control Low pass filters Optical projectors Reliability analysis Signal processing |
| 页码 | 4961-4964 |
| 中文摘要 | Microarray image gridding is one important step of microarray image analysis to determine 2D image coordinates of all array spots in the hybridized gene chip image. Accuracy of microarray image gridding will affect the reliability of gene-chip data extraction and even the final analysis results of gene-chip assays. However, in recent years, many new microarray image gridding methods presented have higher accuracy but have more computation complexity than those precedented ones. To promote gridding accuracy and decrease computation complexity simultaneously, we presented a novel and simple microarray image gridding method based on image projection sequences analysis and local extrema searching. Firstly we transformed 2D microarray image into vertical and horizontal 1D projection sequences, secondly utilized signal processing methods of low pass filtering and zero mean to filtered projection sequences, thirdly computed the first-order difference and second-order difference for the smoothed signals, and finally realized microarray image gridding according to the local extrema of difference sequences and span information of spots array on the microarray image. The subsequent gridding experiments showed that this method had met the requirements of computing accuracy and efficiency of microarray image gridding. |
| 收录类别 | EI |
| 产权排序 | 2 |
| 会议主办者 | Academy of Mathematics and Systems Science; IEEE Robotics and Automation Society; IEEE Control Systems Society; National Natural Science Foundation of China; Chinese Association of Automation |
| 会议录 | WCICA 2012 - Proceedings of the 21th World Congress on Intelligent Control and Automation
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| 会议录出版者 | IEEE |
| 会议录出版地 | Piscataway, NJ, United States |
| 语种 | 英语 |
| ISBN号 | 978-1-4673-1398-8 |
| 源URL | [http://ir.sia.cn/handle/173321/10396]  |
| 专题 | 沈阳自动化研究所_装备制造技术研究室 |
| 推荐引用方式 GB/T 7714 | Liu J,Feng YJ,Liu WJ,et al. A microarray image gridding method based on image projection difference sequences analysis and local extrema searching[C]. 见:10th World Congress on Intelligent Control and Automation, WCICA 2012. Beijing, China. July 6-8, 2012. |
入库方式： OAI收割
来源：沈阳自动化研究所
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