中国科学院机构知识库网格系统: Antibacterial activity of YC-20, a new oxazolidinone

Antibacterial activity of YC-20, a new oxazolidinone

文献类型：期刊论文


作者	Cui, Yingjie ; Dang, Yaxian ; Yang, Yushe; Zhang, Shuhua ; Ji, Ruyun
刊名	JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
出版日期	2006-08
卷号	58 期号:2 页码:452-454
关键词	antibiotics Gram-positive linezolid
ISSN号	0305-7453
DOI	10.1093/jac/dkl254
文献子类	Article
英文摘要	Objectives and methods: YC-20 is a novel oxazolidinone that has targeted activity against Gram-positive bacteria. The in vitro activity of YC-20 and 6 comparators against 522 clinical isolates of Gram-positive species was determined. Results: YC-20 is a potent oxazolidinone with all isolates tested displaying MIC50 and MIC90 values of < 0.5 and 2 mg/L, respectively. MiCs of YC-20 for all isolates tested, with the exception of methicillin-susceptible Staphylococcus epidermidis, were similar or lower than those of linezolid. Conclusions: This study suggests a potential new antibiotic for the treatment of infections with Gram-positive bacteria.
WOS关键词	GRAM-POSITIVE INFECTIONS ; AGENTS
WOS研究方向	Infectious Diseases ; Microbiology ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000239840700035
出版者	OXFORD UNIV PRESS
源URL	[http://119.78.100.183/handle/2S10ELR8/273528]
专题	中国科学院上海药物研究所
通讯作者	Cui, Yingjie
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China 2.Sichuan Ind Inst Antibiot, Chengdu 610051, Peoples R China
推荐引用方式 GB/T 7714	Cui, Yingjie,Dang, Yaxian,Yang, Yushe,et al. Antibacterial activity of YC-20, a new oxazolidinone[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY,2006,58(2):452-454.
APA	Cui, Yingjie,Dang, Yaxian,Yang, Yushe,Zhang, Shuhua,&Ji, Ruyun.(2006).Antibacterial activity of YC-20, a new oxazolidinone.JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY,58(2),452-454.
MLA	Cui, Yingjie,et al."Antibacterial activity of YC-20, a new oxazolidinone".JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 58.2(2006):452-454.

入库方式： OAI收割

来源：上海药物研究所

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Antibacterial activity of YC-20, a new oxazolidinone

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