Cobalt(iii)-catalyzed site-selective C-H amidation of pyridones and isoquinolones
文献类型：期刊论文
| 作者 | Gao, Feng2,3,4; Han, Xu2,3,4; Li, Chunpu2,3; Liu, Lingjun2,5; Cong, Zhanqing1,2; Liu, Hong2,3,4
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2018 |
| 卷号 | 8期号:57页码:32659-32663 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c8ra06716c |
| 文献子类 | Article |
| 英文摘要 | In this study, Cp*Co(iii)-catalyzed site-selective amidation of pyridones and isoquinolones using oxazolones as the amidation reagent is reported. This approach features mild conditions, high efficiency and good functional tolerance. Furthermore, gram-scale preparation and preliminary mechanism experiments were carried out. It provides a straightforward approach for the direct modification of pyridone derivatives. |
| WOS关键词 | C3-SELECTIVE DIRECT ALKYLATION ; CATALYZED DIRECT ARYLATION ; NITRENE TRANSFER-REACTIONS ; BOND ACTIVATION ; MILD CONDITIONS ; ACYL AZIDES ; 2-PYRIDONES ; DERIVATIVES ; ARENES ; FUNCTIONALIZATION |
| 资助项目 | National Natural Science Foundation of China[81620108027] ; National Natural Science Foundation of China[21632008] ; National Natural Science Foundation of China[81602975] ; Major Project of Chinese National Programs for Fundamental Research and Development[2015CB910304] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000448348200029 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272295]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Liu, Hong |
| 作者单位 | 1.ShanghaiTech Univ, Sch Life Sci & Technol, 100 Haike Rd, Shanghai 201210, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China; 4.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China; 5.China Pharmaceut Univ, Sch Pharm, Nanjing 210009, Jiangsu, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Gao, Feng,Han, Xu,Li, Chunpu,et al. Cobalt(iii)-catalyzed site-selective C-H amidation of pyridones and isoquinolones[J]. RSC ADVANCES,2018,8(57):32659-32663. |
| APA | Gao, Feng,Han, Xu,Li, Chunpu,Liu, Lingjun,Cong, Zhanqing,&Liu, Hong.(2018).Cobalt(iii)-catalyzed site-selective C-H amidation of pyridones and isoquinolones.RSC ADVANCES,8(57),32659-32663. |
| MLA | Gao, Feng,et al."Cobalt(iii)-catalyzed site-selective C-H amidation of pyridones and isoquinolones".RSC ADVANCES 8.57(2018):32659-32663. |
入库方式： OAI收割
来源：上海药物研究所
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