Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines
文献类型：期刊论文
| 作者 | Dang, Zhao; Yang, Yushe ; Ji, Ruyun; Zhang, Shuhua
|
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2007-08-15 |
| 卷号 | 17期号:16页码:4523-4526 |
| ISSN号 | 0960-894X |
| 关键词 | fluoroquinolone antibacterial activity piperidine |
| DOI | 10.1016/j.bmcl.2007.05.093 |
| 文献子类 | Article |
| 英文摘要 | The design and synthesis of new fluoroquinolone antibacterial agents having substituted piperidine rings at the C-7 position are described. Most of the new compounds demonstrated high in vitro antibacterial activity. Several of them exhibited significant activities against Gram-positive organisms, which were more potent than those of gemifloxacin, Linezolid, and vancomycin. (c) 2007 Elsevier Ltd. All rights reserved. |
| WOS关键词 | SIDE-EFFECT RELATIONSHIPS ; QUINOLONE ; AGENTS |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| WOS记录号 | WOS:000248877800024 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273176]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yang, Yushe |
| 作者单位 | 1.Sichuan Ind Inst Antibiot, Chengdu 610051, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Dang, Zhao,Yang, Yushe,Ji, Ruyun,et al. Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2007,17(16):4523-4526. |
| APA | Dang, Zhao,Yang, Yushe,Ji, Ruyun,&Zhang, Shuhua.(2007).Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,17(16),4523-4526. |
| MLA | Dang, Zhao,et al."Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 17.16(2007):4523-4526. |
入库方式： OAI收割
来源：上海药物研究所
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