Design and Synthesis of Matrix Metalloprotease Photoaffinity Trimodular Probes
文献类型：期刊论文
| 作者 | Qiu Wenwei1,2,3; Xu Jie3; Li Xin3; Zhong Li3; Li Jingya3 ; Li Jia3; Nan Fajun3
|
| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2009-04 |
| 卷号 | 27期号:4页码:825-833 |
| 关键词 | trimodular probe photoaffinity labeling protein profiling click chemistry matrix metalloprotease |
| ISSN号 | 1001-604X |
| DOI | 10.1002/cjoc.200990138 |
| 文献子类 | Article |
| 英文摘要 | To explore the molecular mechanism of the matrix metalloproteinases (MMPs) in tumor processes, two photoaffinity trimodular probes were designed and synthesized based on the structure activity relationship and the following photoaffinity labelling experiments afforded positive results. |
| WOS关键词 | CANCER-THERAPY ; ANGIOGENESIS ; INHIBITION ; CHEMISTRY ; RECEPTOR |
| 资助项目 | Chinese Academy of Sciences[KSCX1-YW-R-12] ; National Natural Science Foundation of China[30725049] ; National Natural Science Foundation of China[90813037] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3630683 |
| WOS记录号 | WOS:000265717900038 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279275]  |
| 专题 | 国家新药筛选中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物安全性评价中心 |
| 通讯作者 | Li Jia |
| 作者单位 | 1.E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China; 2.E China Normal Univ, Inst Med Chem, Shanghai 200062, Peoples R China 3.Chinese Acad Sci, Chinese Natl Ctr Drug Screening, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Qiu Wenwei,Xu Jie,Li Xin,et al. Design and Synthesis of Matrix Metalloprotease Photoaffinity Trimodular Probes[J]. CHINESE JOURNAL OF CHEMISTRY,2009,27(4):825-833. |
| APA | Qiu Wenwei.,Xu Jie.,Li Xin.,Zhong Li.,Li Jingya.,...&Nan Fajun.(2009).Design and Synthesis of Matrix Metalloprotease Photoaffinity Trimodular Probes.CHINESE JOURNAL OF CHEMISTRY,27(4),825-833. |
| MLA | Qiu Wenwei,et al."Design and Synthesis of Matrix Metalloprotease Photoaffinity Trimodular Probes".CHINESE JOURNAL OF CHEMISTRY 27.4(2009):825-833. |
入库方式： OAI收割
来源：上海药物研究所
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