Improved laboratory synthesis of YC-071, a potent azole antifungal agent
文献类型：期刊论文
| 作者 | Zheng, Yazhou3; Qian, Anran1,2; Ling, Chenyu1,2; Cao, Xufeng1,2; Cui, YongMei3; Yang, Yushe1,2
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| 刊名 | JOURNAL OF CHEMICAL RESEARCH
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| 出版日期 | 2017-04 |
| 期号 | 4页码:241-245 |
| 关键词 | triazole reductive amination intramolecular cyclisation antifungal agent |
| ISSN号 | 1747-5198 |
| DOI | 10.3184/174751917X14902201357419 |
| 文献子类 | Article |
| 英文摘要 | An improved laboratory synthesis of YC-071, a potent azole antifungal agent, has been developed. Compared with the original route, the new route is operationally simple, requiring only limited purification of all the intermediates. The new route is an important scalable synthesis, which meets the need for YC-071 for use in preclinical studies. |
| WOS关键词 | DERIVATIVES ; DISCOVERY ; DESIGN |
| 资助项目 | National Natural Science Foundation of China[21402223] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000416040700013 |
| 出版者 | SCIENCE REVIEWS 2000 LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272708]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Yang, Yushe |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shanghai Univ, Coll Sci, Dept Chem, Shanghai 200444, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zheng, Yazhou,Qian, Anran,Ling, Chenyu,et al. Improved laboratory synthesis of YC-071, a potent azole antifungal agent[J]. JOURNAL OF CHEMICAL RESEARCH,2017(4):241-245. |
| APA | Zheng, Yazhou,Qian, Anran,Ling, Chenyu,Cao, Xufeng,Cui, YongMei,&Yang, Yushe.(2017).Improved laboratory synthesis of YC-071, a potent azole antifungal agent.JOURNAL OF CHEMICAL RESEARCH(4),241-245. |
| MLA | Zheng, Yazhou,et al."Improved laboratory synthesis of YC-071, a potent azole antifungal agent".JOURNAL OF CHEMICAL RESEARCH .4(2017):241-245. |
入库方式： OAI收割
来源：上海药物研究所
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