中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 上海药物研究所
  3. 中国科学院上海药物研究所
  4. 药物化学研究室
(D,L)-10-Camphorsulfonic-Acid-Catalysed Synthesis of Diaryl-Fused 2,8-Dioxabicyclo[3.3.1]nonanes from 2-Hydroxychalcones and Naphthol Derivatives

文献类型：期刊论文

作者Jiang, Xiaolong1,2,3; Song, Zilan2,3; Xu, Chang1; Yao, Qizheng1; Zhang, Ao2,3
刊名EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
出版日期2014-01
期号2页码:418-425
关键词Oxygen heterocycles Nitrogen heterocycles Cyclization Aromatic substitution Fused-ring systems Acid catalysis
ISSN号1434-193X
DOI10.1002/ejoc.201301295
文献子类Article
英文摘要A tandem one-pot Friedel-Crafts alkylation/double cyclization process to conveniently assemble diaryl-fused 2,8-dioxabicyclo[3.3.1]nonanes with aryl substituents at the C-1 position was developed. 2-Hydroxychalcones and naphthol derivatives reacted in refluxing toluene with (D,L)-10-camphorsulfonic acid (CSA) as the catalyst. The transformation conveniently provided the corresponding 2,8-dioxabicyclo[ 3.3.1] nonanes fused with one phenyl and one naphthyl group in moderate to good yields, and various substitutions on both reaction partners were tolerated. More importantly, aryl-and aza-aryl-fused 2,8-dioxabicyclo[3.3.1] nonanes were prepared for the first time using this procedure.
WOS关键词FLAVYLIUM SALTS ; CONDENSATION PRODUCTS ; PROANTHOCYANIDINS ; PHENOLS ; ACID ; 4-HYDROXYCOUMARIN ; CONSTITUENTS ; TUBE
资助项目Distinguished Young Scholars of the Chinese National Science Foundation (NSF)[81125021] ; Distinguished Young Scholars of the Chinese National Science Foundation (NSF)[81373277] ; National Science & Technology Major Project, Key New Drug Creation and Manufacturing Program, China[2012ZX09103-101-035] ; National Science & Technology Major Project, Key New Drug Creation and Manufacturing Program, China[2012ZX09301001-001] ; Interdisciplinary Cooperation Team, Program for Science and Technology Innovation (CAS)[00000000] ; State Key Laboratory of Drug Research[SIMM1302KF-08] ; Shanghai Institute of Materia Medica[00000000]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000336266400018
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/277288]  
专题药物化学研究室
通讯作者Yao, Qizheng
作者单位1.China Pharmaceut Univ, Dept Med Chem, Nanjing 210009, Jiangsu, Peoples R China;
2.SIMM, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China;
3.SIMM, SOMCL, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Jiang, Xiaolong,Song, Zilan,Xu, Chang,et al. (D,L)-10-Camphorsulfonic-Acid-Catalysed Synthesis of Diaryl-Fused 2,8-Dioxabicyclo[3.3.1]nonanes from 2-Hydroxychalcones and Naphthol Derivatives[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2014(2):418-425.
APA Jiang, Xiaolong,Song, Zilan,Xu, Chang,Yao, Qizheng,&Zhang, Ao.(2014).(D,L)-10-Camphorsulfonic-Acid-Catalysed Synthesis of Diaryl-Fused 2,8-Dioxabicyclo[3.3.1]nonanes from 2-Hydroxychalcones and Naphthol Derivatives.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(2),418-425.
MLA Jiang, Xiaolong,et al."(D,L)-10-Camphorsulfonic-Acid-Catalysed Synthesis of Diaryl-Fused 2,8-Dioxabicyclo[3.3.1]nonanes from 2-Hydroxychalcones and Naphthol Derivatives".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .2(2014):418-425.

入库方式： OAI收割

来源：上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。