机构

• 上海药物研究所 [33]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [34]

内容类型

• 期刊论文 [33]
• 会议论文 [1]

发表日期

• 2023 [3]
• 2022 [1]
• 2021 [4]
• 2020 [1]
• 2019 [2]
• 2018 [5]
• 更多

学科主题

筛选

浏览/检索结果: 共34条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221 作者:  Xie, Chenghu;  Liu, Bo;  Song, Zilan;  Yang, Ye;  Dai, Mengdi   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/02/27 Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18 作者:  Tang, Hairong;  Yu, Aisong;  Xing, Li;  Chen, Xiaoyu;  Ding, Huaqian   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 241, 页码: 16 作者:  Shen, Ancheng;  Li, Xiyuan;  Zhang, Yan;  Ma, Jing;  Xiao, Ruoxuan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 Innate immunity  STING Agonists  Structural modification  Immuno-oncology   Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702 作者:  Song, Zilan;  Liu, Bo;  Peng, Xia;  Gu, Wangting;  Sun, Yiming   |  收藏  |  浏览/下载：14/0  |  提交时间：2022/06/15 Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 8 作者:  Song, Zilan;  Liu, Yuting;  Xie, Chenghu;  Tong, Xiankun;  Wang, Xue   |  收藏  |  浏览/下载：82/0  |  提交时间：2021/11/04 Choroquine  Aminochloroquine  Antivirus  Anti-inflammatory  Cytokines   Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17 作者:  Xiao, Xuanzheng;  Lai, Mengzhen;  Song, Zilan;  Geng, Meiyu;  Ding, Jian   |  收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24 KRAS  Covalent inhibitor  Pyridopyrimidinone  Antiproliferative effect  Scaffold hopping   Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 3, 页码: 1649-1669 作者:  Song, Zilan;  Wang, Xiyuan;  Zhang, Yan;  Gu, Wangting;  Shen, Ancheng   |  收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24 Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298 作者:  Ding, Chunyong;  Song, Zilan;  Shen, Ancheng;  Chen, Tingting;  Zhang, Ao   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 Immunotherapy  Anti-tumor  cGAS  STING  TBK1  Small molecule modulators   Discovery of a potent tyrosine kinase AXL inhibitor bearing the 3-((2,3,4,5-tetrahydro-1H-benzo [d] azepin-7-yl)amino)pyrazine core 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 836-838 作者:  Wang, Yueliang;  Xing, Li;  Ji, Yinchun;  Ye, Jiqing;  Dai, Yang   |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 AXL Kinase  Pyrazine  Cancer