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Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine

文献类型：期刊论文

作者Liu, Wenjing1; Mei, Desheng3; Wang, Wei1,2; Duan, Wenhu1,3
刊名TETRAHEDRON LETTERS
出版日期2013-07-17
卷号54期号:29页码:3791-3793
关键词Asymmetric conjugate addition Cinchona alkaloids Enones Chiral primary amine catalysis Nitroalkanes
ISSN号0040-4039
DOI10.1016/j.tetlet.2013.05.019
文献子类Article
英文摘要A cinchona alkaloid derived primary amine catalyzed conjugate addition of nitroalkanes to enones is described. The process affords the Michael adducts in good yield and with up to 99% ee for both acyclic and cyclic enones. (C) 2013 Elsevier Ltd. All rights reserved.
WOS关键词ASYMMETRIC MICHAEL ADDITION ; ALPHA,BETA-UNSATURATED KETONES ; PYRROLIDINE SULFONAMIDE ; CYCLIC ENONES ; ORGANOCATALYST ; NITROOLEFINS ; 9-AMINO-9-DEOXYEPIQUININE ; ALDEHYDES ; NITRO
资助项目Chinese National Natural Science Foundation[81102461] ; Chinese National Natural Science Foundation[81021062] ; Chinese National Natural Science Foundation[90813034] ; Chinese National Programs for High Technology Research and Development[2012AA020302] ; NSF[CHE-1057569]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000324005200016
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/277538]  
专题药物化学研究室
通讯作者Wang, Wei
作者单位1.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;
2.Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA
3.Chinese Acad Sci, Shanghai Inst Mat Med, Dept Med Chem, Shanghai 201203, Peoples R China;
推荐引用方式
GB/T 7714		 Liu, Wenjing,Mei, Desheng,Wang, Wei,et al. Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine[J]. TETRAHEDRON LETTERS,2013,54(29):3791-3793.
APA Liu, Wenjing,Mei, Desheng,Wang, Wei,&Duan, Wenhu.(2013).Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine.TETRAHEDRON LETTERS,54(29),3791-3793.
MLA Liu, Wenjing,et al."Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine".TETRAHEDRON LETTERS 54.29(2013):3791-3793.

入库方式： OAI收割

来源：上海药物研究所

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