SYNTHESIS OF N-(3-CYANO-7-ETHOXY-1,4-DIHYDRO-4-OXOQUINOLIN-6-YL)ACETAMIDE
文献类型：期刊论文
| 作者 | Zhang, Qiang1; Mao, Yongjun1; Liu, Zheng2; Xie, Kai3; Zhu, Yi2; Wei, Yabing3; Jiang, Xiangrui1 ; Shen, Jingshan1,2
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| 刊名 | HETEROCYCLES
 |
| 出版日期 | 2011-12-01 |
| 卷号 | 83期号:12页码:2851-+ |
| 关键词 | 3-Cyanoquinoline Synthesis Reductive Cyclization Condensation Process |
| ISSN号 | 0385-5414 |
| DOI | 10.3987/COM-11-12343 |
| 文献子类 | Article |
| 英文摘要 | New route for the preparation of N-(3-cyano-7-ethoxy-1,4dihydro-4-oxoquinolin-6-yl)acetamide (1), a key intermediate for the synthesis of selective EGFR kinase inhibitors, was described. |
| WOS关键词 | KINASE-ACTIVITY ; INHIBITORS ; OPTIMIZATION ; DISCOVERY ; AGENTS ; HER-2 ; EGFR |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000298213100010 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278312]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Zhang, Qiang |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 2.Topharman Shanghai Co Ltd, Shanghai 201209, Peoples R China; 3.Nanjing Univ Technol, Coll Mat Sci & Engn, Nanjing 210009, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Qiang,Mao, Yongjun,Liu, Zheng,et al. SYNTHESIS OF N-(3-CYANO-7-ETHOXY-1,4-DIHYDRO-4-OXOQUINOLIN-6-YL)ACETAMIDE[J]. HETEROCYCLES,2011,83(12):2851-+. |
| APA | Zhang, Qiang.,Mao, Yongjun.,Liu, Zheng.,Xie, Kai.,Zhu, Yi.,...&Shen, Jingshan.(2011).SYNTHESIS OF N-(3-CYANO-7-ETHOXY-1,4-DIHYDRO-4-OXOQUINOLIN-6-YL)ACETAMIDE.HETEROCYCLES,83(12),2851-+. |
| MLA | Zhang, Qiang,et al."SYNTHESIS OF N-(3-CYANO-7-ETHOXY-1,4-DIHYDRO-4-OXOQUINOLIN-6-YL)ACETAMIDE".HETEROCYCLES 83.12(2011):2851-+. |
入库方式： OAI收割
来源：上海药物研究所
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