机构

• 上海药物研究所 [136]
• 新疆理化技术研究所 [13]
• 生物物理研究所 [1]
• 中国科学院大学 [1]

采集方式

• OAI收割 [150]
• iSwitch采集 [1]

内容类型

• 期刊论文 [151]

发表日期

• 2024 [1]
• 2023 [16]
• 2022 [18]
• 2021 [16]
• 2020 [11]
• 2019 [16]
• 更多

学科主题

• Biochemist... [1]
• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共151条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20 作者:  Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/03/06 CB2R agonist  5-HT1AR agonist  CB1R antagonist  Antidepressant  Anxiolytic   Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids 期刊论文  OAI收割 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2023, 卷号: 185, 页码: 13-25 作者:  Zhao, Chengcheng;  Jiang, Xiangrui;  Peng, Liyuan;  Zhang, Yan;  Li, Huihui   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/01/16 Heart failure  Hypertrophy  Epoxyeicosatrienoic acids  Soluble epoxide hydrolase   Repurposing of Rutan showed effective treatment for COVID-19 disease 期刊论文  OAI收割 FRONTIERS IN MEDICINE, 2023, 卷号: 10, 页码: 13 作者:  Salikhov, Shavkat I.;  Abdurakhmonov, Ibrokhim Y.   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 COVID-19  SARS-CoV-2  3CLpro  RdRp  Rhus coriaria  Rutan  clinical trial   An efficient synthesis of the last step key intermediate for telmisartan via Pd-catalyzed carbonylative cyclization 期刊论文  OAI收割 TETRAHEDRON, 2023, 卷号: 148, 页码: 8 作者:  Odilov, Abdullajon;  Qin, Hongjian;  Bonku, Emmanuel Mintah;  Zhu, Fuqiang;  Yang, Feipu   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/19 Telmisartan  Benzimidazole  Pd-catalyzed  Carbonylative/cyclization   Optimized Synthesis of the Key Intermediate of Telmisartan via the Cyclization of 2-Bromoarylamine with n-Butyronitrile 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2023, 卷号: 27, 期号: 11, 页码: 2165-2173 作者:  Qin, Hongjian;  Mintah Bonku, Emmanuel;  Odilov, Abdullajon;  Wu, Mingjun;  Liu, Yongjian   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/27 bis-benzimidazole  cyclization  2-bromoarylamine  n-butyronitrile  telmisartan  design of experiments   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Comparative study on different extraction methods of oil extract from Mentha asiatica Boriss. and optimization of the extraction process by response surface methodology 期刊论文  OAI收割 FLAVOUR AND FRAGRANCE JOURNAL, 2023, 页码: 12 作者:  Aimila, Aoken;  Xiao, Xiangwen;  Xin, Xuelei;  Sodik, Numonov;  Shen, Jingshan   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 essential oil  extraction methods  GC-MS  in vitro  Mentha asiatica Boriss.  response surface methodology   A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10 作者:  Zhang, Yumin;  Sun, Yuan;  Xie, Yuanchao;  Shang, Weijuan;  Wang, Zhen   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08 Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2023, 页码: 8 作者:  Bonku, Emmanuel Mintah;  Qin, Hongjian;  Odilov, Abdullajon;  Yang, Feipu;  Xing, Xinglong   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 tecovirimat  monkeypox  cycloheptatriene  antiviral drug  reactive distillation   Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13 作者:  Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Peptidomimetics  Benzothiazolyl ketone  3CLpro inhibitor  Pharmacokinetic properties  SARS-CoV-2