Enantioselective Conjugate Addition of N-Heterocycles to alpha,beta-Unsaturated Ketones Catalyzed by Chiral Primary Amines
文献类型：期刊论文
| 作者 | Luo, Guangshun2; Zhang, Shilei2; Duan, Wenhu1,2 ; Wang, Wei2,3
|
| 刊名 | SYNTHESIS-STUTTGART
 |
| 出版日期 | 2009-05-04 |
| 期号 | 9页码:1564-1572 |
| 关键词 | primary amines N-heterocycles enones conjugate addition catalysis |
| ISSN号 | 0039-7881 |
| DOI | 10.1055/s-0029-1216636 |
| 文献子类 | Article |
| 英文摘要 | A new organocatalytic enantioselective conjugate addition reaction of nitrogen-centered heterocycles with alpha,beta-unsaturated ketones has been developed. Promoted by a chiral cinchona alkaloid derived primary amine, the reaction affords the adducts ill moderate to high enantioselectivities. |
| WOS关键词 | AZA-MICHAEL REACTION ; ASYMMETRIC-SYNTHESIS ; CARBONYL-COMPOUNDS ; THIOUREA CATALYST ; ORGANIC-SYNTHESIS ; ORGANOCATALYSIS ; ALDEHYDES ; IMIDES ; NITROOLEFINS ; NITROALKENES |
| 资助项目 | School of Phannacy, East China University of Science Technology[00000000] ; National Science Foundation of China[080103 1005] ; National Science Foundation[CHE-0704015] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000266334000022 |
| 出版者 | GEORG THIEME VERLAG KG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279245]  |
| 专题 | 药物化学研究室 |
| 通讯作者 | Duan, Wenhu |
| 作者单位 | 1.Chinese Acad Sci, Grad Sch, Shanghai Inst Biol Sci, Shanghai Inst Materia Med, Shanghai 201203, Peoples R China; 2.E China Univ Sci & Technol, Sch Pharm, Dept Pharmaceut Sci, Shanghai 200237, Peoples R China; 3.Univ New Mexico, Dept Chem & Biol Chem, Albuquerque, NM 87131 USA |
| 推荐引用方式 GB/T 7714 | Luo, Guangshun,Zhang, Shilei,Duan, Wenhu,et al. Enantioselective Conjugate Addition of N-Heterocycles to alpha,beta-Unsaturated Ketones Catalyzed by Chiral Primary Amines[J]. SYNTHESIS-STUTTGART,2009(9):1564-1572. |
| APA | Luo, Guangshun,Zhang, Shilei,Duan, Wenhu,&Wang, Wei.(2009).Enantioselective Conjugate Addition of N-Heterocycles to alpha,beta-Unsaturated Ketones Catalyzed by Chiral Primary Amines.SYNTHESIS-STUTTGART(9),1564-1572. |
| MLA | Luo, Guangshun,et al."Enantioselective Conjugate Addition of N-Heterocycles to alpha,beta-Unsaturated Ketones Catalyzed by Chiral Primary Amines".SYNTHESIS-STUTTGART .9(2009):1564-1572. |
入库方式： OAI收割
来源：上海药物研究所
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