Cytotoxic activities of some selected medicinal plants of the genus Euphorbia
文献类型：期刊论文
| 作者 | Wang, Xiao-yang2,3; Liu, Li-ping2; Zhu, Rui-xin2; Kang, Ting-guo3; Tong, Ling-jiang1; Xie, Hua1 ; Wang, Hong-bing2,4
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| 刊名 | JOURNAL OF MEDICINAL PLANTS RESEARCH
 |
| 出版日期 | 2011-12-23 |
| 卷号 | 5期号:31页码:6766-6769 |
| 关键词 | Cytotoxic activity Euphorbia human cancer cells |
| ISSN号 | 1996-0875 |
| DOI | 10.5897/JMPR11.1096 |
| 文献子类 | Article |
| 英文摘要 | The present study was undertaken to evaluate the cytotoxic activities of extracts of Euphorbia genus plants, Euphorbia fischeriana, Euphorbia tirucalli, Euphorbia humifusa and Euphorbia antiquorum. The plant selection was based on ethnobotanic information and interviews with local healers. Cytotoxic activities were screened by an in vitro assay system of growth inhibition against two human cancer cell lines, human hepatocyte carcinoma cell (BEL-7402) and human lung cancer cell (A-549). Extracts which exhibited IC50 value less than 30 mu g/ml were considered active. The CHCl3 extracts from E. tirucalli and E. antiquorum exhibited strong cytotoxic effect on the two cell lines. The CHCl3 and EtOAc extracts from E. fischeriana showed significant cytotoxic activity on the A-549 cell. This study revealed that the CHCl3 extracts from E. tirucalli and E. antiquorum, the CHCl3 and EtOAc extracts from E. fischeriana may have a great potential to be exploited for the search of anticancer drug. It is necessary for chemical characterization of the active principles and more extensive biological evaluations. |
| WOS关键词 | ANTIQUORUM ; TIRUCALLI ; DITERPENOIDS ; FISCHERIANA ; TRITERPENE ; LATEX ; ROOTS |
| 资助项目 | National Natural Science Foundation[81001369] ; National Natural Science Foundation[31170327] ; Tongji University of the People's Republic of China[00000000] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000299782000011 |
| 出版者 | ACADEMIC JOURNALS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278300]  |
| 专题 | 药理学第一研究室 |
| 通讯作者 | Wang, Hong-bing |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China; 2.Tongji Univ, Sch Life Sci & Technol, Shanghai 200092, Peoples R China; 3.Liaoning Univ Tradit Chinese Med, Sch Pharm, Dalian, Peoples R China; 4.Tongji Univ, Lishui Inst Tradit Chinese Med, Lishui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xiao-yang,Liu, Li-ping,Zhu, Rui-xin,et al. Cytotoxic activities of some selected medicinal plants of the genus Euphorbia[J]. JOURNAL OF MEDICINAL PLANTS RESEARCH,2011,5(31):6766-6769. |
| APA | Wang, Xiao-yang.,Liu, Li-ping.,Zhu, Rui-xin.,Kang, Ting-guo.,Tong, Ling-jiang.,...&Wang, Hong-bing.(2011).Cytotoxic activities of some selected medicinal plants of the genus Euphorbia.JOURNAL OF MEDICINAL PLANTS RESEARCH,5(31),6766-6769. |
| MLA | Wang, Xiao-yang,et al."Cytotoxic activities of some selected medicinal plants of the genus Euphorbia".JOURNAL OF MEDICINAL PLANTS RESEARCH 5.31(2011):6766-6769. |
入库方式： OAI收割
来源：上海药物研究所
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