Rhodium(III)-catalyzed and MeOH-involved regioselective mono-alkenylation of N-arylureas with acrylates
文献类型：期刊论文
| 作者 | Lv, Honggui1,2,3,4; Shi, Jingjing4 ; Huang, Junjun2,3; Zhang, Chao2,3; Yi, Wei2,3,4
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| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2017-09-14 |
| 卷号 | 15期号:34页码:7088-7092 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c7ob01627a |
| 文献子类 | Article |
| 英文摘要 | We herein disclose, for the first time, Rh(III)-catalyzed and MeOH-involved regioselective mono-alkenylation of arenes with acrylates using NHCONMe2 as the transformable directing group, giving direct access to diverse ortho-acrylated N-phenyl carbamates. The synthetic application of the obtained products to build privileged quinolin-2(1H)-ones and 3-(2-aminophenyl) acrylates has also been demonstrated in subsequent derivatization reactions. |
| WOS关键词 | C-H ACTIVATION ; TRACELESS DIRECTING-GROUP ; RHODIUM-CATALYZED ANNULATION ; CARBOXYLIC-ACIDS ; ROOM-TEMPERATURE ; ALPHA,BETA-UNSATURATED ALDEHYDES ; COUPLING REACTIONS ; C(SP(3))-H BONDS ; DIRECT ARYLATION ; AZOXY COMPOUNDS |
| 资助项目 | NSFC[81502909] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000411454000003 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272483]  |
| 专题 | 药物靶标结构与功能中心 |
| 通讯作者 | Yi, Wei |
| 作者单位 | 1.Shanghai Univ, Dept Chem, 99 Shang Da Rd, Shanghai 200444, Peoples R China 2.Guangzhou Med Univ, Affiliated Hosp 5, Guangzhou 511436, Guangdong, Peoples R China; 3.Guangzhou Med Univ, Key Lab Mol Clin Pharmacol, Guangzhou 511436, Guangdong, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, VARI SIMM Ctr,Ctr Struct & Funct Drug Targets, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Lv, Honggui,Shi, Jingjing,Huang, Junjun,et al. Rhodium(III)-catalyzed and MeOH-involved regioselective mono-alkenylation of N-arylureas with acrylates[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2017,15(34):7088-7092. |
| APA | Lv, Honggui,Shi, Jingjing,Huang, Junjun,Zhang, Chao,&Yi, Wei.(2017).Rhodium(III)-catalyzed and MeOH-involved regioselective mono-alkenylation of N-arylureas with acrylates.ORGANIC & BIOMOLECULAR CHEMISTRY,15(34),7088-7092. |
| MLA | Lv, Honggui,et al."Rhodium(III)-catalyzed and MeOH-involved regioselective mono-alkenylation of N-arylureas with acrylates".ORGANIC & BIOMOLECULAR CHEMISTRY 15.34(2017):7088-7092. |
入库方式： OAI收割
来源：上海药物研究所
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