机构

• 上海药物研究所 [127]

采集方式

• OAI收割 [127]

内容类型

• 期刊论文 [120]
• 会议论文 [7]

发表日期

• 2018 [16]
• 2017 [25]
• 2016 [17]
• 2015 [27]
• 2014 [18]
• 2013 [16]
• 更多

学科主题

筛选

浏览/检索结果: 共127条，第1-10条 帮助 限定条件 专题：药物靶标结构与功能中心    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Disparate impact on CD4 T cell count by two distinct HIV-1 phylogenetic clusters from the same clade 期刊论文  OAI收割 Proceedings of the National Academy of Sciences of the United States of America, 2018 作者:  Song, Hongshuo;  Ou, Weidong;  Feng, Yi;  Zhang, Junli;  Li, Fan   |  收藏  |  浏览/下载：187/0  |  提交时间：2019/01/08 The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine 期刊论文  OAI收割 MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52 作者:  Li, Hong;  Zhao, Lihua;  Singh, Rani;  Ham, J. Nina;  Fadoju, Doris O.   |  收藏  |  浏览/下载：104/0  |  提交时间：2019/01/08 Glucagon receptor  Newborn screening  GCGR mutation  Hyperaminoacidemia  Mahvash disease  Pancreatic alpha cell hyperplasia (ACH)  Pancreatic neuroendocrine tumor (PNET)   Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK) 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 44, 页码: 16994-17007 作者:  Gu, Xin;  Bridges, Michael D.;  Yan, Yan;  de Waal, Parker W.;  Zhou, X. Edward   |  收藏  |  浏览/下载：83/0  |  提交时间：2019/01/08 AMP-activated kinase (AMPK)  biophysics  diabetes  metabolic regulation  cancer  ADaM site  DEER   Structure and Physiological Regulation of AMPK 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 11 作者:  Yan, Yan;  Zhou, X. Edward;  Xu, H. Eric;  Melcher, Karsten   |  收藏  |  浏览/下载：102/0  |  提交时间：2019/01/08 energy metabolism  AMPK  activation loop  AID  -linker  -linker  CBS  LKB1  CaMKK2  RIM   Synthesis of Isoquinolines through Ir-III-Catalyzed C-H Activation/Annulation from Benzimidates with Hydroxylisopropylalkynes 期刊论文  OAI收割 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 期号: 36, 页码: 4991-4995 作者:  Liu, Mingliang;  Gong, Wanchun;  You, Erli;  Zhang, Haizhen;  Shi, Lei   |  收藏  |  浏览/下载：88/0  |  提交时间：2019/01/08 Annulation  C-H activation  Iridium  Nitrogen heterocycles  Synthetic methods   3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 18, 页码: 8136-8154 作者:  Baqi, Younis;  Pillaiyar, Thanigaimalai;  Abdelrahman, Aliaa;  Kaufmann, Olesja;  Aishaibani, Samer   |  收藏  |  浏览/下载：135/0  |  提交时间：2019/01/08 Crystal structure of the Frizzled 4 receptor in a ligand-free state 期刊论文  OAI收割 NATURE, 2018, 卷号: 560, 期号: 7720, 页码: 666-+ 作者:  Yang, Shifan;  Wu, Yiran;  Xu, Ting-Hai;  de Waal, Parker W.;  He, Yuanzheng   |  收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08 Hydroxyl Group-Prompted and Iridium(III)-Catalyzed Regioselective C-H Annulation of N-phenoxyacetamides with Propargyl Alcohols 期刊论文  OAI收割 ADVANCED SYNTHESIS & CATALYSIS, 2018, 卷号: 360, 期号: 13, 页码: 2470-2475 作者:  Chen, Weijie;  Liu, Fu-Xiaomin;  Gong, Wanchun;  Zhou, Zhi;  Gao, Hui   |  收藏  |  浏览/下载：87/0  |  提交时间：2019/01/08 Iridium(III) catalysts  C-H annulation  N-phenoxyacetamides  tertiary propargyl alcohols  benzofurans   Cryo-EM structure of human rhodopsin bound to an inhibitory G protein 期刊论文  OAI收割 NATURE, 2018, 卷号: 558, 期号: 7711, 页码: 553-+ 作者:  Kang, Yanyong;  Kuybeda, Oleg;  de Waal, Parker W.;  Mukherjee, Somnath;  Van Eps, Ned   |  收藏  |  浏览/下载：106/0  |  提交时间：2019/01/08 Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5 期刊论文  OAI收割 Acta pharmacologica Sinica, 2018 作者:  Zhu, Ya;  Zhao, Yan-Long;  Li, Jian;  Liu, Hong;  Zhao, Qiang   |  收藏  |  浏览/下载：67/0  |  提交时间：2019/01/08