Rh(III)-catalyzed and alcohol-involved carbenoid C-H insertion into N-phenoxyacetamides using alpha-diazomalonates
文献类型：期刊论文
| 作者 | Zhou, Jie2,3; Shi, Jingjing2 ; Liu, Xuelei2; Jia, Jinlong2; Song, Huacan3; Xu, H. Eric1,2; Yi, Wei2
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| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2015 |
| 卷号 | 51期号:27页码:5868-5871 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c5cc00354g |
| 文献子类 | Article |
| 英文摘要 | Here we report a new and mild Rh(III)-catalyzed and alcohol-involved carbenoid C-H insertion into N-phenoxyacetamides using alpha-diazomalonates. This reaction provided a straightforward way for installing both an a-quaternary carbon center and a free-OH moiety into the phenyl ring, thus giving access to useful 2-(2-hydroxyphenyl)-2-alkoxymalonates with good substrate/functional group tolerance. |
| WOS关键词 | RHODIUM(III)-CATALYZED ORTHO-ALKENYLATION ; OXIDIZING DIRECTING GROUP ; DIAZO-COMPOUNDS ; EFFICIENT SYNTHESIS ; BOND FORMATION ; DIAZOCARBONYL COMPOUNDS ; INTERNAL OXIDANT ; INDOLE SYNTHESIS ; FACILE SYNTHESIS ; METAL CARBENE |
| 资助项目 | Shanghai Municipal Natural Science Foundation, China[15ZR1447800] ; Chinese Postdoctoral Science Foundation[2012M511158] ; Chinese Postdoctoral Science Foundation[2013T60477] ; Chinese Postdoctoral Science Foundation[2014M560363] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000351660500013 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276739]  |
| 专题 | 药物靶标结构与功能中心 |
| 通讯作者 | Xu, H. Eric |
| 作者单位 | 1.Van Andel Res Inst, Lab Struct Sci, Program Struct Biol & Drug Discovery, Grand Rapids, MI 49503 USA 2.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Ctr Struct & Funct Drug Targets,VARI SIMM Ctr, Shanghai 201203, Peoples R China; 3.Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhou, Jie,Shi, Jingjing,Liu, Xuelei,et al. Rh(III)-catalyzed and alcohol-involved carbenoid C-H insertion into N-phenoxyacetamides using alpha-diazomalonates[J]. CHEMICAL COMMUNICATIONS,2015,51(27):5868-5871. |
| APA | Zhou, Jie.,Shi, Jingjing.,Liu, Xuelei.,Jia, Jinlong.,Song, Huacan.,...&Yi, Wei.(2015).Rh(III)-catalyzed and alcohol-involved carbenoid C-H insertion into N-phenoxyacetamides using alpha-diazomalonates.CHEMICAL COMMUNICATIONS,51(27),5868-5871. |
| MLA | Zhou, Jie,et al."Rh(III)-catalyzed and alcohol-involved carbenoid C-H insertion into N-phenoxyacetamides using alpha-diazomalonates".CHEMICAL COMMUNICATIONS 51.27(2015):5868-5871. |
入库方式： OAI收割
来源：上海药物研究所
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