One-pot cascade synthesis of N-methoxyisoquinolinediones via Rh(III)-catalyzed carbenoid insertion C-H activation/cyclization
文献类型：期刊论文
| 作者 | Shi, Jingjing1 ; Zhou, Jie1,3; Yan, Yunnan1; Jia, Jinlong1; Liu, Xuelei1; Song, Huacan3; Xu, H. Eric1,2; Yi, Wei1
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| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2015 |
| 卷号 | 51期号:4页码:668-671 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c4cc08407a |
| 文献子类 | Article |
| 英文摘要 | Here a new, mild and versatile method for one-pot cascade synthesis of diverse N-methoxyisoquinolinediones via Rh(III)-catalyzed regioselective carbenoid insertion C-H activation/cyclization of N-methoxybenzamides with a-diazotized Meldrum's acid has been achieved. Extension of the developed Rh(III) catalysis for building new analogs of the marketed drug Edaravone has also been demonstrated. |
| WOS关键词 | VIRUS TYPE-1 INTEGRASE ; BOND ACTIVATION ; DIAZO-COMPOUNDS ; EFFICIENT SYNTHESIS ; ROOM-TEMPERATURE ; FACILE SYNTHESIS ; METAL CARBENE ; FUNCTIONALIZATION ; DERIVATIVES ; ALKYNES |
| 资助项目 | Jay and Betty Van Andel Foundation, Amway (China)[00000000] ; Chinese Postdoctoral Science Foundation[2012M511158] ; Chinese Postdoctoral Science Foundation[2013T60477] ; Chinese Postdoctoral Science Foundation[2014M560363] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000346166600011 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276786]  |
| 专题 | 药物靶标结构与功能中心 |
| 通讯作者 | Xu, H. Eric |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, VARI SIMM Ctr,Ctr Struct & Funct Drug Targets, Shanghai 201203, Peoples R China; 2.Van Andel Res Inst, Program Struct Biol & Drug Discovery, Lab Struct Sci, Grand Rapids, MI 49503 USA 3.Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Shi, Jingjing,Zhou, Jie,Yan, Yunnan,et al. One-pot cascade synthesis of N-methoxyisoquinolinediones via Rh(III)-catalyzed carbenoid insertion C-H activation/cyclization[J]. CHEMICAL COMMUNICATIONS,2015,51(4):668-671. |
| APA | Shi, Jingjing.,Zhou, Jie.,Yan, Yunnan.,Jia, Jinlong.,Liu, Xuelei.,...&Yi, Wei.(2015).One-pot cascade synthesis of N-methoxyisoquinolinediones via Rh(III)-catalyzed carbenoid insertion C-H activation/cyclization.CHEMICAL COMMUNICATIONS,51(4),668-671. |
| MLA | Shi, Jingjing,et al."One-pot cascade synthesis of N-methoxyisoquinolinediones via Rh(III)-catalyzed carbenoid insertion C-H activation/cyclization".CHEMICAL COMMUNICATIONS 51.4(2015):668-671. |
入库方式： OAI收割
来源：上海药物研究所
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