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Rhodium(III)-Catalyzed Redox-Neutral [3+3] Annulation of N-nitrosoanilines with Cyclopropenones: A Traceless Approach to Quinolin-4(1H)-One Scaffolds

文献类型：期刊论文

作者Liu, Lingjun1,2,3,4; Li, Jiyuan1,4; Dai, Wenhao1,2,3,4; Gao, Feng1,4; Chen, Kaixian1,2,3,4,5; Zhou, Yu1,4; Liu, Hong1,2,3,4,5
刊名MOLECULES
出版日期2020-01-02
卷号25期号:2页码:15
关键词Rhodium(III) redox-neutral [3+3] annulation N-nitrosoaniline cyclopropenones quinolin-4(1H)-ones
DOI10.3390/molecules25020268
通讯作者Chen, Kaixian(kxchen@simm.ac.cn) ; Zhou, Yu(zhouyu@simm.ac.cn) ; Liu, Hong(hliu@simm.ac.cn)
英文摘要A traceless approach to quinolin-4(1H)-one scaffolds through Rh(III)-catalyzed redox-neutral [3+3] cyclization of N-nitrosoanilines with cyclopropenones has been achieved. This protocol features short reaction time and atom-economical combination without extra additives, which can be further applied in the construction of privileged heterocyclic compounds in pharmaceutical chemistry.
WOS关键词C-H ACTIVATION ; INDOLE SYNTHESIS ; BOND ; DERIVATIVES ; ACYLATION ; NITROSO ; EXPLORATION ; OLEFINATION ; CYCLIZATION ; VERSATILE
资助项目National Natural Science Foundation of China[21672232] ; National Natural Science Foundation of China[21977106] ; National Natural Science Foundation of China[81620108027] ; National S & T Major Projects[2018ZX09711002] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12040217]
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
语种英语
WOS记录号WOS:000515381800030
出版者MDPI
源URL[http://119.78.100.183/handle/2S10ELR8/281117]  
专题新药研究国家重点实验室
通讯作者Chen, Kaixian; Zhou, Yu; Liu, Hong
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China
2.China Pharmaceut Univ, State Key Lab Nat Med, 24 Tong Jia Xiang, Nanjing 210009, Peoples R China
3.China Pharmaceut Univ, Dept Med Chem, 24 Tong Jia Xiang, Nanjing 210009, Peoples R China
4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China
5.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Lingjun,Li, Jiyuan,Dai, Wenhao,et al. Rhodium(III)-Catalyzed Redox-Neutral [3+3] Annulation of N-nitrosoanilines with Cyclopropenones: A Traceless Approach to Quinolin-4(1H)-One Scaffolds[J]. MOLECULES,2020,25(2):15.
APA Liu, Lingjun.,Li, Jiyuan.,Dai, Wenhao.,Gao, Feng.,Chen, Kaixian.,...&Liu, Hong.(2020).Rhodium(III)-Catalyzed Redox-Neutral [3+3] Annulation of N-nitrosoanilines with Cyclopropenones: A Traceless Approach to Quinolin-4(1H)-One Scaffolds.MOLECULES,25(2),15.
MLA Liu, Lingjun,et al."Rhodium(III)-Catalyzed Redox-Neutral [3+3] Annulation of N-nitrosoanilines with Cyclopropenones: A Traceless Approach to Quinolin-4(1H)-One Scaffolds".MOLECULES 25.2(2020):15.

入库方式： OAI收割

来源：上海药物研究所

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