ga3anewgambogicacidderivativeexhibitspotentantitumoractivitiesinvitroviaapoptosisinvolvedmechanisms
文献类型：期刊论文
| 作者 | Hua XIE ; Yuxin QIN; Yunlong ZHOU; Linjiang TONG; Liping LIN; Meiyu GENG; Wenhu DUAN; Jian DING
|
| 刊名 | actapharmacologicasinica
 |
| 出版日期 | 2009 |
| 卷号 | 30期号:3页码:346 |
| 关键词 | DRUG DISCOVERY CELLS BAX PROTEIN TRANSLOCATION CYTOTOXICITY PATHWAY BINDING DOMAIN DEATH gambogic acid GA3 antitumor apoptosis caspase Bcl-2 cytochrome c |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2009.3 |
| 英文摘要 | Aim: Gambogic acid (GA) is the major active ingredient of gamboge, which is secreted from a Chinese traditional medicine, Garcinia hanburyi, which possesses potent antitumor activity. GA3, a new GA derivative, has been shown to possess better water solubility than GA. The aim of the present study was to examine the antitumor activity of GA3 and the mechanism underlying it. |
| 资助项目 | [National Natural Science Foundation of China] ; [Shanghai Postdoctoral Grant] |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/283899]  |
| 专题 | 中国科学院上海药物研究所 |
| 作者单位 | 中国科学院上海药物研究所 |
| 推荐引用方式 GB/T 7714 | Hua XIE,Yuxin QIN,Yunlong ZHOU,et al. ga3anewgambogicacidderivativeexhibitspotentantitumoractivitiesinvitroviaapoptosisinvolvedmechanisms[J]. actapharmacologicasinica,2009,30(3):346. |
| APA | Hua XIE.,Yuxin QIN.,Yunlong ZHOU.,Linjiang TONG.,Liping LIN.,...&Jian DING.(2009).ga3anewgambogicacidderivativeexhibitspotentantitumoractivitiesinvitroviaapoptosisinvolvedmechanisms.actapharmacologicasinica,30(3),346. |
| MLA | Hua XIE,et al."ga3anewgambogicacidderivativeexhibitspotentantitumoractivitiesinvitroviaapoptosisinvolvedmechanisms".actapharmacologicasinica 30.3(2009):346. |
入库方式： OAI收割
来源：上海药物研究所
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