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浏览/检索结果: 共422条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   pH-responsive nanogels with enhanced antioxidant and antitumor activities on drug delivery and smart drug release 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 257, 页码: 16 作者:  Ma, Bing;  Li, Qing;  Mi, Yingqi;  Zhang, Jingjing;  Tan, Wenqiang   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 Benzimidazole-chitosan quaternary ammonium  salt  Nanogels  pH-responsive  Antioxidant activity  Antitumor activity   Extracellular Matrix-Trapped Bioinspired Lipoprotein Prolongs Tumor Retention to Potentiate Antitumor Immunity 期刊论文  OAI收割 ADVANCED MATERIALS, 2024, 页码: 14 作者:  Wu, Yao;  Li, Yongping;  Hu, Zixin;  Li, Yuan;  Zhang, Shixuan   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/02/27 antitumor responses  bioinspired lipoprotein  extracellular matrix  pomalidomide  tumor retention   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Breaking Tumor Immunosuppressive Network by Regulating Multiple Nodes with Triadic Drug Delivery Nanoparticles 期刊论文  OAI收割 ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 17826-17844 作者:  Yan, Wenlu;  Li, Yu;  Zou, Yiting;  Zhu, Runqi;  Wu, Ting   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 triple-negative breast cancer  antitumor immunity  tumor-associated macrophages  myeloid-derived suppressorcells  immune network  nanoparticle   Preparation of imidazole acids grafted chitosan with enhanced antioxidant, antibacterial and antitumor activities 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2023, 卷号: 315, 页码: 16 作者:  Ma, Bing;  Zhang, Jingjing;  Mi, Yingqi;  Miao, Qin;  Tan, Wenqiang   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/11/15 Imidazole acids grafted chitosan  Antioxidant activity  Antibacterial activity  Antitumor activity   Construction of Diversified Penta-Spiro-Heterocyclic and Fused-Heterocyclic Frameworks with Potent Antitumor Activity 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 7 作者:  Liu, Qi;  Liu, Xuyi;  Li, Yazhou;  Zhou, Yu;  Zhao, Linxiang   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/10/17 spiro  fused-heterocyclic frameworks  substrate- and pH- controlled strategies  C-H activation  [4+1] and [4+2] annulation  antitumor  indazolone   Structure-Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 9 作者:  Shen, Chang;  Xu, Peijia;  Zhang, Changfa;  Su, Zhaoming;  Shan, Bin   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 cGAS-STING signaling pathway  STING agonists  antitumor immunity  anti-infection immunity   Antitumor Cembrane Diterpenoids from the South China Sea Soft Coral Lobophytum sp. 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2023, 卷号: 20, 期号: 4 作者:  Song, Yu-Ting;  Yu, Dan-Dan;  Zhi Su, Ming;  Luo, Hui;  Cao, Jian-Guo   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 soft coral  Lobophytum sp  cembranoids  configuration determination  antitumor activity   Spatial-Drug-Laden Protease-Activatable M1 Macrophage System Targets Lung Metastasis and Potentiates Antitumor Immunity 期刊论文  OAI收割 ACS NANO, 2023, 卷号: 17, 期号: 6, 页码: 5354-5372 作者:  Xu, Xiaoxuan;  Wang, Qiang;  Qian, Xindi;  Wu, Yao;  Wang, Jiaoying   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 M1 macrophages  lung metastasis  antitumor immunity  fibroblast activation protein protease  liposome