Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong
文献类型：期刊论文
| 作者 | Chen, Xiao-Cui1,8,10; Cao, Jun-Ji2; Ward, Tony J.3; Tian, Lin-Wei4; Ning, Zhi5; Gali, Nirmal Kumar5; Aquilina, Noel J.6; Yim, Steve Hung-Lam1,9; Qu, Linli11; Ho, Kin-Fai1,7 |
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2020-11-10 |
| 卷号 | 742页码:12 |
| 关键词 | Commuter exposure Black carbon Transition metals Cytotoxicity Reactive oxygen species (ROS) |
| ISSN号 | 0048-9697 |
| DOI | 10.1016/j.scitotenv.2020.140501 |
| 通讯作者 | Ho, Kin-Fai(kfho@cuhk.edu.hk) |
| 英文摘要 | Epidemiological studies have demonstrated significant associations between traffic-related air pollution and adverse health outcomes. Personal exposure to fine particles (PM2.5) in transport microenvironments and their toxicological properties remain to be investigated. Commuter exposures were investigated in public transport systems (including the buses and Mass Transit Railway (MTR)) along two sampling routes in Hong Kong. Real-time sampling for PM2.5 and black carbon (BC), along with integrated PM2.5 sampling, were performed during the warm and cold season of 2016-2017, respectively. Commuter exposure to BC during 3-hour commuting time exhibited a wider range, from 3.4 to 4.6 mu g/m(3) on the bus and 5.5 to 8.7 mu g/m(3) in MTR cabin (p < .05). PM2.5 mass andmajor chemical constituents (including organic carbon (OC), elemental carbon (EC), andmetals) were analyzed. Cytotoxicity, including cellular reactive oxygen species (ROS) production, was determined in addition to acellular ROS generation. PM2.5 treatment promoted the ROS generation in a concentration-dependent manner. Consistent diurnal variationswere observed for commuter exposure to BC and PM2.5 components, along with cellular and acellular ROS generation, which marked with two peaks during the morning (08:00-11:00) and evening rush hours (17:30-20:30). Commuter exposures in the MTR system were characterized by higher levels of PM2.5 and elemental components (e.g., Ca, Cr, Fe, Zn, Ba) compared to riding the bus, alongwith higher cellular and acellular ROS production (p < .01). These metals were attributed to different sources: rail tracks, wheels, brakes, and crustal origin. Weak to moderate associations were shown for the analyzed transition metals with PM2.5-induced cell viability and cellular ROS. Multiple linear regression analysis revealed that Ni, Zn, Mn, Fe, Ti, and Co attributed to cytotoxicity and ROS generation. These findings underscore the importance of commuter exposures and their toxic effects, urging effective mitigating strategies to protect human health. (C) 2020 Elsevier B.V. All rights reserved. |
| WOS关键词 | PARTICULATE AIR-POLLUTION ; PERSONAL EXPOSURE ; OXIDATIVE STRESS ; TRANSPORT MICROENVIRONMENTS ; ELEMENTAL COMPOSITION ; MATTER PM ; COARSE ; ASSOCIATIONS ; VARIABILITY ; BIOMARKERS |
| 资助项目 | Research Grants Council of The Hong Kong Special Administrative Region of China[14202817] ; Research Grants Council of The Hong Kong Special Administrative Region of China[14212116] ; Research Grants Council of The Hong Kong Special Administrative Region of China[412413] |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000569416600009 |
| 出版者 | ELSEVIER |
| 资助机构 | Research Grants Council of The Hong Kong Special Administrative Region of China |
| 源URL | [http://ir.ieecas.cn/handle/361006/15295]  |
| 专题 | 地球环境研究所_粉尘与环境研究室 |
| 通讯作者 | Ho, Kin-Fai |
| 作者单位 | 1.Chinese Univ Hong Kong, Inst Environm Energy & Sustainabil, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Earth Environm, Key Lab Aerosol, SKLLQG, Xian, Peoples R China 3.Univ Montana, Sch Publ & Community Hlth Sci, Missoula, MT 59812 USA 4.Univ Hong Kong, Sch Publ Hlth, Hong Kong, Peoples R China 5.Hong Kong Univ Sci & Technol, Div Environm & Sustainabil, Hong Kong, Peoples R China 6.Univ Malta, Dept Geosci, MSD-2080 Msida, Malta 7.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China 8.Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Peoples R China 9.Chinese Univ Hong Kong, Dept Geog & Resource Management, Hong Kong, Peoples R China 10.Univ Hong Kong, Hlth High Dens Cities Lab, HKUrbanLab, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Xiao-Cui,Cao, Jun-Ji,Ward, Tony J.,et al. Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,742:12. |
| APA | Chen, Xiao-Cui.,Cao, Jun-Ji.,Ward, Tony J..,Tian, Lin-Wei.,Ning, Zhi.,...&Ho, Kin-Fai.(2020).Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong.SCIENCE OF THE TOTAL ENVIRONMENT,742,12. |
| MLA | Chen, Xiao-Cui,et al."Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong".SCIENCE OF THE TOTAL ENVIRONMENT 742(2020):12. |
入库方式： OAI收割
来源：地球环境研究所
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