Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011
文献类型：期刊论文
| 作者 | Bao, Jie1; Li, Xiu-Xiu1; He, Fei1; Zhang, Xiaoyong3; Zhu, Kongkai1; Tao, Hongrui1,2; Yu, Jin-Hai1; Liu, Haishan1; Zhang, Hua1 |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2020-08-06 |
| 卷号 | 61期号:32页码:6 |
| 关键词 | Aspergillus terreus Asperbutenolide A Butyrolactone Butenolide |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2020.152193 |
| 通讯作者 | Zhang, Hua(bio_zhangh@ujn.edu.cn) |
| 英文摘要 | Two new aromatic butenolides (1 and 2), along with a known analogue (3), were isolated and structurally identified from the fermentation extract of a mangrove sediment derived fungus Aspergillus terreus SCAU011. Structures of the new compounds were established mainly by spectroscopic data analyses, and the absolute configurations were determined by a combination of various strategies including electronic circular dichroism (ECD) comparison, induced circular dichroism (LCD) experiments and chemical derivation and degradation. Compound 2, with an unusual dimeric scaffold linked via an ether bridge, exhibited a wide range of biological properties including strong cyclooxygenase-2 (COX-2) and alpha-glucosidase inhibitory activities, as well as moderate antiradical and antibacterial effects. (C) 2020 Elsevier Ltd. All rights reserved. |
| WOS关键词 | ENDOPHYTIC FUNGUS ; ABSOLUTE-CONFIGURATION ; BUTYROLACTONE DERIVATIVES ; ASPERNOLIDES ; MO-2(OAC)(4) ; 1,2-DIOLS |
| 资助项目 | Program for Innovative Research Team in University[IRT-16R19] ; Natural Science Foundation of Shandong Province[JQ201721] ; Young Taishan Scholars Program[tsqn20161037] ; Shandong Talents Team Cultivation Plan of University Preponderant Discipline[10027] ; Project of Shandong Province Higher Educational Science and Technology Program[J18KA255] ; Foundation of University of Jinan[XBS160100393] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000551671900004 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/292178]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhang, Hua |
| 作者单位 | 1.Univ Jinan, Sch Biol Sci & Technol, Jinan 250022, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 3.South China Agr Univ, Coll Marine Sci, Guangzhou 510642, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bao, Jie,Li, Xiu-Xiu,He, Fei,et al. Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011[J]. TETRAHEDRON LETTERS,2020,61(32):6. |
| APA | Bao, Jie.,Li, Xiu-Xiu.,He, Fei.,Zhang, Xiaoyong.,Zhu, Kongkai.,...&Zhang, Hua.(2020).Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011.TETRAHEDRON LETTERS,61(32),6. |
| MLA | Bao, Jie,et al."Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011".TETRAHEDRON LETTERS 61.32(2020):6. |
入库方式： OAI收割
来源：上海药物研究所
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