机构

• 上海药物研究所 [34]

采集方式

• OAI收割 [34]

内容类型

• 期刊论文 [34]

发表日期

• 2023 [2]
• 2022 [1]
• 2021 [3]
• 2020 [3]
• 2019 [6]
• 2018 [6]
• 更多

学科主题

筛选

浏览/检索结果: 共34条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Ligand recognition and G protein coupling of the human itch receptor MRGPRX1 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 12 作者:  Guo, Lulu;  Zhang, Yumu;  Fang, Guoxing;  Tie, Lu;  Zhuang, Yuming   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/16 PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1 期刊论文  OAI收割 MedComm, 2023, 卷号: 4, 期号: 2, 页码: e245 作者:  Xie, Fei;  Zhang, Han;  Zhu, Kongkai;  Jiang, Cheng-Shi;  Zhang, Xiaoya   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/26 Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis 期刊论文  OAI收割 ADVANCED SCIENCE, 2022, 卷号: 9, 期号: 7, 页码: 2103228 作者:  Mao, Jianhua;  Zhu, Kongkai;  Long, Zhangbiao;  Zhang, Huimin;  Xiao, Bing   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/21 antithrombotic target  bleeding risk  E97A knock-in mice  small molecule  beta 3/Src interaction   Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207 作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens   |  收藏  |  浏览/下载：84/0  |  提交时间：2021/08/17 Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9 作者:  Liu, Shan-Kui;  Hao, Haifang;  Bian, Yuan;  Ge, Yong-Xi;  Lu, Shengyuan   |  收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24 α  -glycosidase  virtual screening  cytotoxicity  type 2 diabetes  molecular docking   Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 10 作者:  Fan, Yafei;  Chen, Hangfei;  Mu, Ning;  Wang, Wengui;  Zhu, Kongkai   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 Nosiheptide analogues  Semi-synthesis  Antimicrobial activity  Molecular docking   Asperbutenolide A, an unusual aromatic butenolide dimer with diverse bioactivities from a marine-derived fungus Aspergillus terreus SCAU011 期刊论文  OAI收割 TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 32, 页码: 6 作者:  Bao, Jie;  Li, Xiu-Xiu;  He, Fei;  Zhang, Xiaoyong;  Zhu, Kongkai   |  收藏  |  浏览/下载：19/0  |  提交时间：2020/12/24 Aspergillus terreus  Asperbutenolide A  Butyrolactone  Butenolide   Spiroalanpyrroids A and B, sesquiterpene alkaloids with a unique spiro-eudesmanolide-pyrrolizidine skeleton from Inula helenium 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 2, 页码: 303-309 作者:  Cai, You-Sheng;  Wu, Zi;  Zheng, Xiao-Qin;  Wang, Cong;  Wang, Jian-Rong   |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63 作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 polycomb repressive complex 2  EZH2-EED interaction inhibitor  virtual screening  molecular dynamics simulation   Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文  OAI收割 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785 作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 PRMT5 inhibitor  Anti-proliferative  Cellular target validation  Design and synthesis