Brassinosteroid analogues from the fruiting bodies of Laetiporus sulphureus and their anti-inflammatory activity
文献类型：期刊论文
| 作者 | Khalilov, Q (Khalilov, Qosimjon)[ 1,2,3 ]; Li, LY (Li, Liya)[ 4 ]; Liu, YS (Liu, Yushuang)[ 1,2,3 ]; Liu, W (Liu, Wei)[ 1,2,3 ]; Numonov, S (Numonov, Sodik)[ 1,2,5 ]; Aisa, HA (Aisa, Haji Akber)[ 1,2 ] ; Yuan, T (Yuan, Tao)[ 1,2 ]
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| 刊名 | STEROIDS
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| 出版日期 | 2019 |
| 卷号 | 151期号:11页码:1-4 |
| 关键词 | Laetiporus sulphureus Polyporaceae Brassinosteroid Anti-inflammatory RAW264.7 |
| ISSN号 | 0039-128X |
| DOI | 10.1016/j.steroids.2019.108468 |
| 英文摘要 | Three new brassinosteroid analogues, named sulphurenolide A, sulphurenolide B and sulphurenolide C, were isolated from the methanolic extract of fruiting bodies of Laetiporus sulphureus. Their structures were established on the basis of extensive spectroscopic analysis (1D, 2D NMR, and HRESIMS) and ECD calculation. Sulphurenolides A and B are a pair of C-20 epimer, and sulphurenolide B represents the first naturally occurring 20R-brassinosteroid. Moreover, sulphurenolides A C are firstly reported 5-hydroxylation and homo-6-oxa derivatives of brassinosteroids from natural sources. Anti-inflammatory assay revealed that sulphurenolides B and C exhibited significant inhibitory effects on NO production in lipopolysaccharide-induced RAW264.7 cells, and sulphurenolide C showed stronger inhibition than that of positive control, minocycline. |
| WOS记录号 | WOS:000505649700013 |
| 源URL | [http://ir.xjipc.cas.cn/handle/365002/7836]  |
| 专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
| 通讯作者 | Aisa, HA (Aisa, Haji Akber)[ 1,2 ]; Yuan, T (Yuan, Tao)[ 1,2 ] |
| 作者单位 | 1.Chinese Tajik Innovat Ctr Nat Prod, Dushanbe 734063, Tajikistan 2.Northeastern Univ, Coll Life & Hlth Sci, Inst Microbial Pharmaceut, Shenyang 110819, Peoples R China 3.Univ Chinese Acad Sci, Beijing 10009, Peoples R China 4.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Xinjiang Indigenous Med Plants Reso, Urumqi 830011, Peoples R China 5.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Khalilov, Q ,Li, LY ,Liu, YS ,et al. Brassinosteroid analogues from the fruiting bodies of Laetiporus sulphureus and their anti-inflammatory activity[J]. STEROIDS,2019,151(11):1-4. |
| APA | Khalilov, Q .,Li, LY .,Liu, YS .,Liu, W .,Numonov, S .,...&Yuan, T .(2019).Brassinosteroid analogues from the fruiting bodies of Laetiporus sulphureus and their anti-inflammatory activity.STEROIDS,151(11),1-4. |
| MLA | Khalilov, Q ,et al."Brassinosteroid analogues from the fruiting bodies of Laetiporus sulphureus and their anti-inflammatory activity".STEROIDS 151.11(2019):1-4. |
入库方式： OAI收割
来源：新疆理化技术研究所
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