Cyclic dipeptides: Biological activities and self-assembled materials
文献类型：期刊论文
| 作者 | Zhao, Kaili1,2; Xing, Ruirui1,2; Yan, Xuehai1,2 |
| 刊名 | PEPTIDE SCIENCE
 |
| 出版日期 | 2020-10-10 |
| 页码 | 13 |
| 关键词 | antibacterial antitumor diketopiperazine optical waveguiding self-assembly |
| ISSN号 | 2475-8817 |
| DOI | 10.1002/pep2.24202 |
| 英文摘要 | Cyclic dipeptides (CDPs) are the smallest cyclic peptides containing 2,5-diketopiperazine rings. CDPs have advantages of structures and properties, including excellent hydrogen-bonding-forming ability (two hydrogen bonding acceptors and two hydrogen bonding donors), structural rigidity, and enzymatic stability, which make CDPs potential candidates as core scaffolds for drug discovery and building blocks for self-assembly. In this review, we focus on distinctive bioactivities of CDPs, such as antitumor, antimicrobial, antivirus and antioxidant, and self-assembly properties of CDPs and their derivatives. Emphasis will be placed on the thermodynamics and kinetics CDPs self-assembly and applications of self-assembled materials. This review provides insight into the development of CDPs and their corresponding assembled materials as drug delivery carriers and optoelectronic materials. |
| WOS关键词 | RHABDITID ENTOMOPATHOGENIC NEMATODE ; SOLID-PHASE ; ASPERGILLUS-FUMIGATUS ; MEDICINAL CHEMISTRY ; IN-VITRO ; DIKETOPIPERAZINES ; PEPTIDE ; 2,5-DIKETOPIPERAZINES ; TRYPROSTATINS ; BACTERIA |
| 资助项目 | National Natural Science Foundation of China[21802144] ; Key Research Program of Frontier Sciences of Chinese Academy of Sciences[QYZDB-SSW-JSC034] ; Innovation Research Community Science Fund[21821005] ; National Natural Science Fund BRICS STI Framework Program[51861145304] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| WOS记录号 | WOS:000579329300001 |
| 出版者 | WILEY |
| 资助机构 | National Natural Science Foundation of China ; Key Research Program of Frontier Sciences of Chinese Academy of Sciences ; Innovation Research Community Science Fund ; National Natural Science Fund BRICS STI Framework Program |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/42423]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Xing, Ruirui; Yan, Xuehai |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Chem Engn, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Kaili,Xing, Ruirui,Yan, Xuehai. Cyclic dipeptides: Biological activities and self-assembled materials[J]. PEPTIDE SCIENCE,2020:13. |
| APA | Zhao, Kaili,Xing, Ruirui,&Yan, Xuehai.(2020).Cyclic dipeptides: Biological activities and self-assembled materials.PEPTIDE SCIENCE,13. |
| MLA | Zhao, Kaili,et al."Cyclic dipeptides: Biological activities and self-assembled materials".PEPTIDE SCIENCE (2020):13. |
入库方式： OAI收割
来源：过程工程研究所
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