Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity
文献类型：期刊论文
| 作者 | Kamoldinov, Khamidulla1,2; Li, Jun1,2; Eshbakova, Komila3; Sagdullaev, Shamansur3; Xu, Gaoya4; Zhou, Yubo4 ; Li, Jia4,5; Aisa, Haji Akber1,2
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| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2021-07-01 |
| 卷号 | 187页码:7 |
| 关键词 | Ferula samarkandica Korovin Apiaceae Samarcandicins A-I Sesquiterpene coumarin Cytotoxity MV-4-11 cell Mino cell |
| ISSN号 | 0031-9422 |
| DOI | 10.1016/j.phytochem.2021.112705 |
| 通讯作者 | Li, Jia() ; Aisa, Haji Akber(aisa@ms.xjb.ac.cn) |
| 英文摘要 | Phytochemical study on the ethanolic extract of the dried roots of Ferula samarkandica Korovin led to the isolation of nine undiscribed sesquiterpene coumarins, samarcandicins A-I, along with thirteen known sesquiterpene coumarins. Their structures were characterized by detailed spectroscopic analysis including NMR and HR-ESI-MS. Mogoltacin and nevskin exhibited high inhibitory activity against MV-4-11 cell with IC50 values of 3.94 +/- 0.06 mu M and 3.87 +/- 0.10 mu M, respectively, and nevskin and feshurin showed high inhibitory activity against mino cell with IC50 values of 1.48 +/- 0.06 mu M and 7.88 +/- 0.60 mu M, respectively. |
| WOS关键词 | SEEDS |
| 资助项目 | National Natural Science Foundation of China[U1703235] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000654130400001 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/297259]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Li, Jia; Aisa, Haji Akber |
| 作者单位 | 1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Beijing South Rd 40-1, Urumqi 830011, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Beijing South Rd 40-1, Urumqi 830011, Peoples R China 3.Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Prosp M Ulugbeka 83, Tashkent, Uzbekistan 4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 5.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Kamoldinov, Khamidulla,Li, Jun,Eshbakova, Komila,et al. Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity[J]. PHYTOCHEMISTRY,2021,187:7. |
| APA | Kamoldinov, Khamidulla.,Li, Jun.,Eshbakova, Komila.,Sagdullaev, Shamansur.,Xu, Gaoya.,...&Aisa, Haji Akber.(2021).Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity.PHYTOCHEMISTRY,187,7. |
| MLA | Kamoldinov, Khamidulla,et al."Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity".PHYTOCHEMISTRY 187(2021):7. |
入库方式： OAI收割
来源：上海药物研究所
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