Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities
文献类型：期刊论文
| 作者 | Nuermaimaiti, Muaitaer1,2; Turak, Ablajan2; Yang, Qing3,4; Tang, Bixi3,5; Zang, Yi3,6 ; Li, Jia3,6,7; Aisa, Haji Akber2
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2021-10-01 |
| 卷号 | 154页码:7 |
| ISSN号 | 0367-326X |
| 关键词 | Artemisia sieversiana Dimeric guaianolides Sesquiterpenes Anti-inflammatory |
| DOI | 10.1016/j.fitote.2021.104996 |
| 通讯作者 | Aisa, Haji Akber(haji@ms.xjb.ac.cn) |
| 英文摘要 | Eight undescribed sesquiterpenes, including three dimeric guaianolides and five sesquiterpens, together with ten known ones, were isolated from the aerial parts of Artemisia sieversiana. Their structures were elucidated by extensive spectroscopic techniques and ECD calculation. The isolated compounds were tested for their anti-inflammatory effects against IL-1 beta, IL-6 and TNF-alpha in LPS-induced RAW 264.7 cells. Compounds 4, 9, 12, 15, 16 and 17 showed potent anti-inflammatory activities. |
| WOS关键词 | DIMERIC GUAIANOLIDES ; DERIVATIVES ; LACTONES |
| 资助项目 | Xinjiang International Science & Technology Cooperation Program[2019E01017] ; National Natural Science Foundation of China[U1703235] ; National Natural Science Foundation of China[31900291] ; Youth Innovation Promotion Association CAS |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| WOS记录号 | WOS:000703820600003 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/297478]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Aisa, Haji Akber |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 4.Nanchang Univ, Sch Pharm, Dept Pharmacol, Nanchang 330006, Jiangxi, Peoples R China 5.Fudan Univ, Sch Pharm, China Dept Pharmacol, Shanghai 201203, Peoples R China 6.UCAS, Hangzhou Inst Adv Study, Sch Pharmaceut Sci & Technol, Hangzhou 310024, Peoples R China 7.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Nuermaimaiti, Muaitaer,Turak, Ablajan,Yang, Qing,et al. Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities[J]. FITOTERAPIA,2021,154:7. |
| APA | Nuermaimaiti, Muaitaer.,Turak, Ablajan.,Yang, Qing.,Tang, Bixi.,Zang, Yi.,...&Aisa, Haji Akber.(2021).Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities.FITOTERAPIA,154,7. |
| MLA | Nuermaimaiti, Muaitaer,et al."Sesquiterpenes from Artemisia Sieversiana and their anti-inflammatory activities".FITOTERAPIA 154(2021):7. |
入库方式： OAI收割
来源：上海药物研究所
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