Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity
文献类型：期刊论文
| 作者 | Kamoldinov, K (Kamoldinov, Khamidulla) 1 , 2; Li, J (Li, Jun) 1 , 2; Eshbakova, K (Eshbakova, Komila) 3; Sagdullaev, S (Sagdullaev, Shamansur) 3; Xu, GY (Xu, Gaoya) 4; Zhou, YB (Zhou, Yubo) 4; Li, J (Li, Jia) 4 , 5; Aisa, HA (Aisa, Haji Akber) 1 , 2
|
| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2021 |
| 卷号 | 187期号:7页码:1-7 |
| 关键词 | Ferula samarkandica KorovinApiaceaeSamarcandicins A-ISesquiterpene coumarinCytotoxityMV-4-11 cellMino cell |
| DOI | 10.1016/j.phytochem.2021.112705 |
| 英文摘要 | Phytochemical study on the ethanolic extract of the dried roots of Ferula samarkandica Korovin led to the isolation of nine undiscribed sesquiterpene coumarins, samarcandicins A-I, along with thirteen known sesquiterpene coumarins. Their structures were characterized by detailed spectroscopic analysis including NMR and HR-ESI-MS. Mogoltacin and nevskin exhibited high inhibitory activity against MV-4-11 cell with IC50 values of 3.94 +/- 0.06 mu M and 3.87 +/- 0.10 mu M, respectively, and nevskin and feshurin showed high inhibitory activity against mino cell with IC50 values of 1.48 +/- 0.06 mu M and 7.88 +/- 0.60 mu M, respectively. |
| WOS记录号 | WOS:000654130400001 |
| 源URL | [http://ir.xjipc.cas.cn/handle/365002/7860]  |
| 专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
| 通讯作者 | Aisa, HA (Aisa, Haji Akber) 1 , 2 |
| 作者单位 | 1.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Prosp M Ulugbeka 83, Tashkent, Uzbekistan 4.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Beijing South Rd 40-1, Urumqi 830011, Peoples R China 5.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Beijing South Rd 40-1, Urumqi 830011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Kamoldinov, K ,Li, J ,Eshbakova, K ,et al. Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity[J]. PHYTOCHEMISTRY,2021,187(7):1-7. |
| APA | Kamoldinov, K .,Li, J .,Eshbakova, K .,Sagdullaev, S .,Xu, GY .,...&Aisa, HA .(2021).Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity.PHYTOCHEMISTRY,187(7),1-7. |
| MLA | Kamoldinov, K ,et al."Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity".PHYTOCHEMISTRY 187.7(2021):1-7. |
入库方式： OAI收割
来源：新疆理化技术研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。