Detecting CD20-Rituximab interaction forces using AFM single-molecule force spectroscopy
文献类型：期刊论文
| 作者 | Li M(李密) ; Liu LQ(刘连庆); Wang YC(王越超); Dong ZL(董再励); Li GY(李广勇); Xiao XB(肖秀斌); Zhang WJ(张伟京)
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| 刊名 | CHINESE SCIENCE BULLETIN
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| 出版日期 | 2011 |
| 卷号 | 56期号:35页码:3829-3835 |
| 关键词 | Atomic Force Microscopy Single-molecule Force Spectroscopy Non-hodgkin's Lymphoma Monoclonal Antibody |
| ISSN号 | 1001-6538 |
| 产权排序 | 1 |
| 英文摘要 | The invention of atomic force microscopy(AFM) has provided new technology for measuring specific molecular interaction forces.Using AFM single-molecule force spectroscopy(SMFS) techniques,CD20-Rimximab rupture forces were measured on purified CD20 proteins,Raji cells,and lymphoma patient B cells.Rimximab molecules were linked onto AFM tips using AFM probe functionalization technology,and purified CD20 proteins were attached to mica using substrate functionalization technology. |
| WOS关键词 | Anti-cd20 Monoclonal-antibodies ; Living Cells ; Recognition Events ; Microscopy ; Localization ; Surfaces |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000297745800014 |
| 公开日期 | 2012-05-29 |
| 源URL | [http://ir.sia.cn/handle/173321/7338]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 通讯作者 | Liu LQ(刘连庆); Wang YC(王越超) |
| 作者单位 | 1.Graduate University of Chinese Academy of Sciences, Beijing, China 2.Department of Lymphoma, Affiliated Hospital of Military Medical Academy of Sciences, Beijing, China 3.Department of Electrical and Computer Engineering, University of Pittsburgh, Pittsburgh, USA 4.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China 5.Department of Electrical and Computer Engineering, Michigan State University, East Lansing, USA |
| 推荐引用方式 GB/T 7714 | Li M,Liu LQ,Wang YC,et al. Detecting CD20-Rituximab interaction forces using AFM single-molecule force spectroscopy[J]. CHINESE SCIENCE BULLETIN,2011,56(35):3829-3835. |
| APA | Li M.,Liu LQ.,Wang YC.,Dong ZL.,Li GY.,...&Zhang WJ.(2011).Detecting CD20-Rituximab interaction forces using AFM single-molecule force spectroscopy.CHINESE SCIENCE BULLETIN,56(35),3829-3835. |
| MLA | Li M,et al."Detecting CD20-Rituximab interaction forces using AFM single-molecule force spectroscopy".CHINESE SCIENCE BULLETIN 56.35(2011):3829-3835. |
入库方式： OAI收割
来源：沈阳自动化研究所
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