Investigating the mechanical cues involved in virus–cell interactions opens novel possibilities for understanding the underlying mechanisms guiding viral infection, which will have great impacts on virology and human health. The threat from viruses to human health is increasingly severe, and new deadly viruses are constantly discovered in the world, including severe acute respiratory syndrome-related coronavirus, severe acute respiratory syndrome coronavirus 2, Middle East respiratory syndrome-related coronavirus (MERS-CoV), Zika virus (ZIKV), Ebola virus, avian influenza virus, and so on [1–3], which pose unprecedented burden to human society. Hence, investigating the detailed processes...