Engineering Biological Tissues from the Bottom-Up: Recent Advances and Future Prospects
文献类型:期刊论文
作者 | Wang, Xiaowen1; Wang, Zhen1; Zhai, Wenya3; Wang, Fengyun1; Ge ZX(葛治星)2; Yu HB(于海波)2; Yang WG(杨文广)1 |
刊名 | Micromachines |
出版日期 | 2022 |
卷号 | 13期号:1页码:1-40 |
ISSN号 | 2072-666X |
关键词 | Bottom-up tissue engineering Drug screening Micro-fabrication Modular assembly |
产权排序 | 3 |
英文摘要 | Tissue engineering provides a powerful solution for current organ shortages, and researchers have cultured blood vessels, heart tissues, and bone tissues in vitro. However, traditional top-down tissue engineering has suffered two challenges: Vascularization and reconfigurability of functional units. With the continuous development of micro-nano technology and biomaterial technology, bottom-up tissue engineering as a promising approach for organ and tissue modular reconstruction has gradually developed. In this article, relevant advances in living blocks fabrication and assembly techniques for creation of higher-order bioarchitectures are described. After a critical overview of this technology, a discussion of practical challenges is provided, and future development prospects are proposed. |
WOS关键词 | CELL-LADEN MICROGELS ; MICROENGINEERED HYDROGELS ; MULTICELLULAR SPHEROIDS ; MICROSCALE HYDROGELS ; RAPID FORMATION ; LIQUID BRIDGE ; FABRICATION ; SURFACES ; SYSTEM ; SHEETS |
WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Instruments & Instrumentation ; Physics |
语种 | 英语 |
WOS记录号 | WOS:000747288900001 |
资助机构 | National Key R&D Program of China (Project No. 2018YFB1304900) ; National Natural Science Foundation of China (Project No. 61803323) ; Shandong Province Natural Science Foundation (Project No. ZR2019BF049 and No. ZR2020ME147) ; Key Research Program of Frontier Science (QYZDB-SSW-JSC008) ; Joint fund of Science & Technology Department of Liaoning Province and State Key Laboratory of Robotics (Project No. 2021-KF-22-03) |
源URL | [http://ir.sia.cn/handle/173321/30306] |
专题 | 沈阳自动化研究所_机器人学研究室 |
通讯作者 | Yang WG(杨文广) |
作者单位 | 1.School of Electromechanical and Automotive Engineering, Yantai University, Yantai 264005, China 2.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China 3.School of Energy and Materials Engineering, Shandong Polytechnic College, Jining 272000, China |
推荐引用方式 GB/T 7714 | Wang, Xiaowen,Wang, Zhen,Zhai, Wenya,et al. Engineering Biological Tissues from the Bottom-Up: Recent Advances and Future Prospects[J]. Micromachines,2022,13(1):1-40. |
APA | Wang, Xiaowen.,Wang, Zhen.,Zhai, Wenya.,Wang, Fengyun.,Ge ZX.,...&Yang WG.(2022).Engineering Biological Tissues from the Bottom-Up: Recent Advances and Future Prospects.Micromachines,13(1),1-40. |
MLA | Wang, Xiaowen,et al."Engineering Biological Tissues from the Bottom-Up: Recent Advances and Future Prospects".Micromachines 13.1(2022):1-40. |
入库方式: OAI收割
来源:沈阳自动化研究所
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