Multiple local assignment rules are common in production lines with complex production elements to direct the production process. Different local assignment rules have different degrees of impact on each production evaluation index, which aggravates the conflict between each production evaluation index. In order to solve the problem of increasing conflict among multiple production evaluation indexes in complex production scheduling process, based on the mathematical model of flexible flow shop with limited buffer and public buffer (FFSP-PB), game elements such as game player, game strategy and game order are established according to the idea of multiplayer cooperative game, and design the corresponding game strategy selection method to predict and control the game behavior of each player in the problem. Then a conflict resolution method of production evaluation index based on multiplayer cooperative game is proposed to solve the conflict between multiple production evaluation indexes, and then improve each production evaluation index. Finally, according to the actual production data of a bus manufacturing enterprise based on flexible manufacturing mode, several simulation schemes are designed to analyze and verify the effectiveness and practicability of the proposed method in resolving the conflicts between production evaluation indexes, and provides a reliable new solution for the conflict resolution of production evaluation index in the field of flexible manufacturing.