With the continuous development of the mining industry and the continuous advancement of science and technology, increasing new technical methods have been applied in the field of mine safety. In order to solve the problems of backwardness and inefficiency in the traditional disaster avoidance methods of mines, a three-dimensional modeling technique was used to establish a mixed reality model of disaster avoidance in Yanqianshan mine. Subsequently, based on the Floyd algorithm, the overall disaster avoidance line of the underground mine was dynamically optimized, and the man-machine interaction mode and holographic display in mixed reality technology were realized. Finally, in cooperation with HoloLens wearable MR equipment, an underground mine emergency escape system was successfully established. The research results show that the system provides a new solution to the safety of underground mines and can assist underground mine workers well in emergency escape process.