The single crystal superalloy SRR99 experimental samples were single point treated by laser shock peening (LSP) with laser pulse energy of 5–7 J. The surface morphology, micro-hardness, surface residual stress and surface microstructure of samples prior and after LSP were determined by corresponding characterization instrument. From the surface morphology, a circular pit was formed in surface, which due to the severe plastic deformation induced by LSP, and the diameter & maximum relative height of circular pit were increase with laser pulse energy. From the micro-hardness and residual stress test results of samples, these were increased after LSP treatment. In detail, the initial microhardness and residual stress were 398 HV and -498 MPa, with laser pulse energy of 5 J, the microhardness and residual stress were increased to 455 HV and -843 MPa, when the laser pulse energy was increased to 7 J, the microhardness and residual stress were increased to 512 HV and -942 MPa. In addition, the surface roughness of samples was increased too, which reflect the severe plastic deformation. By observing the microscopic morphology of the bottom of the pit, it is found that there are convex structure and crater shape defect structures on the bottom surface, and the formation of these structures may affect the surface roughness of the shock area. Although LSP caused certain degree of twist deformation of the shape of the γ' phase, the original strengthening method characteristics of the matrix phase and strengthening phase was not destroyed, which still maintained the creep strength and thermal fatigue properties of superalloy. The experiment show that LSP can cause significant work hardening effect on the surface of superalloy, and the generated high residual compressive stress can effectively delay the initiation and propagation of cracks. Therefore, LSP technology can effectively improve the fatigue life of single crystal blade components.