Exposure to novel and legacy per- and polyfluoroalkyl substances (PFASs) and associations with type 2 diabetes: A case-control study in East China
文献类型：期刊论文
| 作者 | Han, Xu; Meng, Lingling; Zhang, Gaoxin; Li, Yingming; Shi, Yali; Zhang, Qinghua; Jiang, Guibin
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| 刊名 | ENVIRONMENT INTERNATIONAL
 |
| 出版日期 | 2021 |
| 卷号 | 289页码:- |
| 关键词 | Polychloro-1 3-butadienes Hexachlorobutadiene Shellfish Fish Gas chromatography-triple quadrupole mass spectrometry |
| ISSN号 | 0269-7491 |
| 英文摘要 | Polychloro-1,3-butadienes (polyCBDs) are attracting increasing concern due to their high toxicity. However, research on multiple polyCBDs in aquatic biota is still extremely limited. In this study, a sensitive method for simultaneous determination of nine polyCBD (Cl4-Cl6) congeners, including six tetrachlorobutadiene (TeCBD) isomers, two pentachlorobutadiene (PeCBD) isomers, and hexachlorobutadiene (HCBD), in shellfish was developed based on accelerated solvent extraction (ASE), solid-phase extraction (SPE) clean-up and gas chromatography-triple quadrupole mass spectrometry (GC-QqQ-MS/MS). Low method limits of detection (MDLs) in the range 0.03-0.21 ng/g dry weight for target analytes with satisfactory recoveries (47.7 %-70.6 %) were achieved. The valid method was then applied to analyze nine polyCBDs congeners in 42 shellfish and 11 fish samples collected from markets in eight coastal cities, China. Trace HCBD was detected in 14 samples, while TeCBDs and PeCBDs were under the MDLs in all the samples, indicating little contamination of these pollutants in the marketed shellfish and fish in China. Multiple polyCBDs especially TeCBDs and PeCBDs were firstly involved in the proposed method and investigation here, which lay the groundwork for future research on the environmental behavior and exposure risks of polyCBDs in aquatic biotas. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/46804]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Sinopec, Res Inst Petr Proc, Beijing 100083, Peoples R China 2.Res Ctr Ecoenvironm Sci, Chinese Acad Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 3.Shandong First Med Univ, Hosp Affiliated 1, Shandong Prov Qianfoshan Hosp, Jinan 250014, Shandong, Peoples R China 4.Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.[Zhang, Qinghua 7.Jiang, Guibin 8.UCAS, Hangzhou Inst Adv Study, Inst Environm & Hlth, Hangzhou 310000, Zhejiang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Han, Xu,Meng, Lingling,Zhang, Gaoxin,et al. Exposure to novel and legacy per- and polyfluoroalkyl substances (PFASs) and associations with type 2 diabetes: A case-control study in East China[J]. ENVIRONMENT INTERNATIONAL,2021,289:-. |
| APA | Han, Xu.,Meng, Lingling.,Zhang, Gaoxin.,Li, Yingming.,Shi, Yali.,...&Jiang, Guibin.(2021).Exposure to novel and legacy per- and polyfluoroalkyl substances (PFASs) and associations with type 2 diabetes: A case-control study in East China.ENVIRONMENT INTERNATIONAL,289,-. |
| MLA | Han, Xu,et al."Exposure to novel and legacy per- and polyfluoroalkyl substances (PFASs) and associations with type 2 diabetes: A case-control study in East China".ENVIRONMENT INTERNATIONAL 289(2021):-. |
入库方式： OAI收割
来源：生态环境研究中心
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