Lignans and Phenylethanoid Glycosides from the Aerial Parts of Pogostemon cablin
文献类型：期刊论文
| 作者 | Chen, Jiaying1; Han, Linhang1; Li, Guangxia1,2; Sun, Liqin1,2; Qian, Fei2; Chen, Kaixian1,3 ; Zhang, Liuqiang1; Li, Yiming1
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| 刊名 | CHEMISTRY & BIODIVERSITY
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| 出版日期 | 2022-12-05 |
| 页码 | 12 |
| ISSN号 | 1612-1872 |
| 关键词 | Pogostemon cablin lignans phenylethanoid glycosides ECD anti-inflammatory activities |
| DOI | 10.1002/cbdv.202200889 |
| 通讯作者 | Zhang, Liuqiang(ymlius@163.com) ; Li, Yiming(04100217@163.com) |
| 英文摘要 | Two new lignans (1-2) and a new octaketide (12), together with twenty-nine known compounds (3-11, 13-32) were isolated and identified from the aerial part of Pogostemon cablin. Their chemical structures were revealed mainly through NMR and MS data. The absolute configuration of 1 and 2 was deduced by comparing its experimental CD with the calculated ECD spectra. The inhibitory activities of the isolated compounds on LPS-stimulated nitric oxide (NO) production in RAW 264.7 cells were investigated. At a concentration of 25 mu M, compounds 1 and 11 showed approximately equal NO inhibitory effects to that of aminoguanidine. |
| WOS关键词 | PHENYLPROPANOID GLYCOSIDE ; AQUEOUS EXTRACT ; ROOTS ; CONSTITUENTS ; ESTERS ; BENTH. |
| 资助项目 | National Natural Science Foundation of China[81973458] ; National Natural Science Foundation of China[81903889] ; Opening Foundation of National Facility for Translational Medicinal (Shanghai)[TMSK-2021-404] ; program of Shanghai E-research Institute of Bioactive Constituents in Traditional Chinese Medicine[E14017] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000897605800001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/304177]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhang, Liuqiang; Li, Yiming |
| 作者单位 | 1.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Inst Interdisciplinary Integrat Med Res, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Jiaying,Han, Linhang,Li, Guangxia,et al. Lignans and Phenylethanoid Glycosides from the Aerial Parts of Pogostemon cablin[J]. CHEMISTRY & BIODIVERSITY,2022:12. |
| APA | Chen, Jiaying.,Han, Linhang.,Li, Guangxia.,Sun, Liqin.,Qian, Fei.,...&Li, Yiming.(2022).Lignans and Phenylethanoid Glycosides from the Aerial Parts of Pogostemon cablin.CHEMISTRY & BIODIVERSITY,12. |
| MLA | Chen, Jiaying,et al."Lignans and Phenylethanoid Glycosides from the Aerial Parts of Pogostemon cablin".CHEMISTRY & BIODIVERSITY (2022):12. |
入库方式： OAI收割
来源：上海药物研究所
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