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  4. 黄土与第四纪地质国家重点实验室（2010~）
Ancient DNA and deep population structure in sub-Saharan African foragers

文献类型：期刊论文

作者Lipson, Mark36,37; Sawchuk, Elizabeth A.34,35; Thompson, Jessica C.32,33; Oppenheimer, Jonas31; Tryon, Christian A.28,29,30; Ranhorn, Kathryn L.32; de Luna, Kathryn M.27; Sirak, Kendra A.36,37; Olalde, Inigo26,37; Ambrose, Stanley H.38
刊名NATURE
出版日期2022-02-23
页码24
ISSN号0028-0836
DOI10.1038/s41586-022-04430-9
通讯作者Lipson, Mark(mlipson@genetics.med.harvard.edu) ; Sawchuk, Elizabeth A.(esawchuk@ualberta.ca) ; Thompson, Jessica C.(jessica.thompson@yale.edu) ; Reich, David(reich@genetics.med.harvard.edu) ; Prendergast, Mary E.(mary@rice.edu)
英文摘要Multiple lines of genetic and archaeological evidence suggest that there were major demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of sub-Saharan Africa(1-4). Inferences about this period are challenging to make because demographic shifts in the past 5,000 years have obscured the structures of more ancient populations(3,5). Here we present genome-wide ancient DNA data for six individuals from eastern and south-central Africa spanning the past approximately 18,000 years (doubling the time depth of sub-Saharan African ancient DNA), increase the data quality for 15 previously published ancient individuals and analyse these alongside data from 13 other published ancient individuals. The ancestry of the individuals in our study area can be modelled as a geographically structured mixture of three highly divergent source populations, probably reflecting Pleistocene interactions around 80-20 thousand years ago, including deeply diverged eastern and southern African lineages, plus a previously unappreciated ubiquitous distribution of ancestry that occurs in highest proportion today in central African rainforest hunter-gatherers. Once established, this structure remained highly stable, with limited long-range gene flow. These results provide a new line of genetic evidence in support of hypotheses that have emerged from archaeological analyses but remain contested, suggesting increasing regionalization at the end of the Pleistocene epoch. DNA analysis of 6 individuals from eastern and south-central Africa spanning the past approximately 18,000 years, and of 28 previously published ancient individuals, provides genetic evidence supporting hypotheses of increasing regionalization at the end of the Pleistocene.
WOS关键词HUNTER-GATHERERS ; GENOME SEQUENCE ; STONE-AGE ; HISTORY ; MIGRATION ; ADMIXTURE ; ORIGIN ; MTDNA ; CAVE ; TREE
资助项目NSF Archaeometry programme[BCS-1460369] ; National Geographic Society[NGS-53412R-18] ; Yale University ; Hyde Family Foundations ; Social Sciences and Humanities Research Council of Canada[756-2017-0456] ; Social Sciences and Humanities Research Council of Canada[BPF 169449] ; Radcliffe Institute for Advanced Study ; NIH[R01-GM100233] ; NIH[R01-HG012287] ; John Templeton Foundation[61220] ; Allen Discovery Center programme, a Paul G. Allen Frontiers Group advised programme of the Paul G. Allen Family Foundation
WOS研究方向Science & Technology - Other Topics
语种英语
出版者NATURE PORTFOLIO
WOS记录号WOS:000760257200004
资助机构NSF Archaeometry programme ; National Geographic Society ; Yale University ; Hyde Family Foundations ; Social Sciences and Humanities Research Council of Canada ; Radcliffe Institute for Advanced Study ; NIH ; John Templeton Foundation ; Allen Discovery Center programme, a Paul G. Allen Frontiers Group advised programme of the Paul G. Allen Family Foundation
源URL[http://ir.ieecas.cn/handle/361006/17511]  
专题地球环境研究所_黄土与第四纪地质国家重点实验室（2010~）
通讯作者Lipson, Mark; Sawchuk, Elizabeth A.; Thompson, Jessica C.; Reich, David; Prendergast, Mary E.
作者单位1.Harvard Med Sch, Howard Hughes Med Inst, Boston, MA 02115 USA
2.Broad Inst Harvard & MIT, Cambridge, MA 02142 USA
3.Univ Calif Santa Barbara, Dept Anthropol, Santa Barbara, CA USA
4.Univ Vienna, Human Evolut & Archaeol Sci HEAS, Vienna, Austria
5.Univ Vienna, Dept Evolutionary Anthropol, Vienna, Austria
6.Arizona State Univ, Sch Human Evolut & Social Change, Tempe, AZ USA
7.Chinese Acad Sci, Inst Earth Environm, State Key Lab Loess & Quaternary Geol, Xian, Peoples R China
8.Univ Oslo, Dept Archeol Conservat & Hist, Oslo, Norway
9.Univ Algarve, Interdisciplinary Ctr Archeol & Evolut Human Beha, FCHS, Faro, Portugal
10.Natl Museums Kenya, Dept Earth Sci, Nairobi, Kenya
推荐引用方式
GB/T 7714		 Lipson, Mark,Sawchuk, Elizabeth A.,Thompson, Jessica C.,et al. Ancient DNA and deep population structure in sub-Saharan African foragers[J]. NATURE,2022:24.
APA Lipson, Mark.,Sawchuk, Elizabeth A..,Thompson, Jessica C..,Oppenheimer, Jonas.,Tryon, Christian A..,...&Prendergast, Mary E..(2022).Ancient DNA and deep population structure in sub-Saharan African foragers.NATURE,24.
MLA Lipson, Mark,et al."Ancient DNA and deep population structure in sub-Saharan African foragers".NATURE (2022):24.

入库方式： OAI收割

来源：地球环境研究所

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