Antimicrobial and Antitumor Activities of Crude Extracts and Isolated Compounds from Euphorbia humifusa
文献类型：期刊论文
| 作者 | Lin Jianbo; Zhao Haiqing; Hang Ba; Aisa Haji Akber
|
| 刊名 | ASIAN JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 25期号:7页码:3957-3960 |
| 关键词 | Euphorbia humifusa Ethyl acetate extract Antimicrobial activity Antitumor activity |
| ISSN号 | 0970-7077 |
| 通讯作者 | Aisa, HA |
| 中文摘要 | Euphorbia humifusa Willd. has been used in traditional Chinese medicine. Herein we report the isolation of its constituents and the testing results of their antimicrobial and antitumor activities. The results show that the crude petroleum ether, chloroform, ethyl acetate, butanol and residual methanol fractions exert such activities. Particularly, the crude petroleum ether and ethyl acetate fractions exhibit antigrowth activity against Staphyloccocus aureus with MIC 0.5 mg/mL. Petroleum ether and chloroform fractions significantly exhibit potent antigrowth activity against Caco-2 cells, with IC50 value of 0.059 and 0.025 mg/mL, respectively. The promising bioactivities of the crude petroleum ether fractions guided the first isolation of compounds: 24-methylene cycloartanone (2), dibutyl phthalate (3), hexacosanol (4) and bis-(2-ethylhexyl) phthalate (5) from this species. The antimicrobial activities of compounds 1-2 were evaluated. The tested compounds exhibit potent antigrowth activity against Staphyloccocus aureus, Escherichia coli and Canidia albicans. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| 资助信息 | China National Funds for Distinguished Young Scientists 30925045; CAS/SAFEA International Partnership Program for Creative Research Teams |
| 公开日期 | 2013-11-07 |
| 源URL | [http://ir.xjipc.cas.cn/handle/365002/2646]  |
| 专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
| 作者单位 | Chinese Acad Sci, Key Lab Chem Plant Resources Arid Reg, Xinjiang Tech Inst Phys & Chem, Urumqi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin Jianbo,Zhao Haiqing,Hang Ba,et al. Antimicrobial and Antitumor Activities of Crude Extracts and Isolated Compounds from Euphorbia humifusa[J]. ASIAN JOURNAL OF CHEMISTRY,2013,25(7):3957-3960. |
| APA | Lin Jianbo,Zhao Haiqing,Hang Ba,&Aisa Haji Akber.(2013).Antimicrobial and Antitumor Activities of Crude Extracts and Isolated Compounds from Euphorbia humifusa.ASIAN JOURNAL OF CHEMISTRY,25(7),3957-3960. |
| MLA | Lin Jianbo,et al."Antimicrobial and Antitumor Activities of Crude Extracts and Isolated Compounds from Euphorbia humifusa".ASIAN JOURNAL OF CHEMISTRY 25.7(2013):3957-3960. |
入库方式： OAI收割
来源：新疆理化技术研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。