Motor assessment of developing common marmosets
文献类型：期刊论文
| 作者 | Wang, YW ; Fang, Q ; Gong, N |
| 刊名 | NEUROSCIENCE BULLETIN
 |
| 出版日期 | 2014 |
| 卷号 | 30期号:3页码:387-393 |
| ISSN号 | 1673-7067 |
| 关键词 | PARKINSONS-DISEASE NONHUMAN PRIMATE MODEL GENERATION DEFICITS |
| 通讯作者 | Gong, N (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Neurosci, Shanghai 200031, Peoples R China.,ngong@ion.ac.cn |
| 英文摘要 | Motor development has been extensively studied in human infants and children, with several established scales for the evaluation of motor functions. However, the study of the neuronal mechanisms underlying human motor development is hampered by the lack of good animal models. The common marmoset (Callithrix jacchus), a small New World monkey, has recently attracted much attention as a potential nonhuman primate model for understanding human physiology and diseases. However, little is known about its gross motor development. In the present study, we found that marmosets have a critical period for motor development in postnatal weeks 2 to 5, and acquire most of their motor skills by 8 weeks of age. We also developed methods to assess their motor functions, which will be useful for the evaluation of motor performance in marmoset models of human diseases. In addition, we found that marmosets exhibit a "head-to-tail" sequence of motor development similar to that found in humans, further supporting the notion that they provide a good animal model for studying the neuronal mechanisms underlying human motor development. |
| 学科主题 | Neurosciences |
| 资助信息 | Youth Innovation Promotion Association of the Chinese Academy of Sciences; SA-SIBS scholarship; MoST 973 Program of China [2011CBA00400]; Strategic Priority Research Program of the CAS [XDB02020100] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2014-07-30 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/2605]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Wang, YW,Fang, Q,Gong, N. Motor assessment of developing common marmosets[J]. NEUROSCIENCE BULLETIN,2014,30(3):387-393. |
| APA | Wang, YW,Fang, Q,&Gong, N.(2014).Motor assessment of developing common marmosets.NEUROSCIENCE BULLETIN,30(3),387-393. |
| MLA | Wang, YW,et al."Motor assessment of developing common marmosets".NEUROSCIENCE BULLETIN 30.3(2014):387-393. |
入库方式： OAI收割
来源：上海神经科学研究所
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