A modified light-dark box test for the common marmoset
文献类型：期刊论文
| 作者 | Wang, YW ; Fang, Q ; Gong, N |
| 刊名 | NEUROSCIENCE BULLETIN
 |
| 出版日期 | 2014 |
| 卷号 | 30期号:3页码:394-400 |
| 关键词 | ANXIETY CONFRONTATION DIAZEPAM BEHAVIOR MODELS RATS FEAR |
| ISSN号 | 1673-7067 |
| 通讯作者 | Gong, N (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Neurosci, Shanghai 200031, Peoples R China.,ngong@ion.ac.cn |
| 英文摘要 | The common marmoset (Callithrix jacchus) has attracted extensive attention for use as a non-human primate model in biomedical research, especially in the study of neuropsychiatric disorders. However, behavioral test methods are still limited in the field of marmoset research. The light-dark box is widely used for the evaluation of anxiety in rodents, but little is known about light-dark preference in marmosets. Here, we modified the light-dark test to study this behavior. The modified apparatus consisted of three compartments: one transparent open area and two closed opaque compartments. The closed compartments could be dark or light. We found that both adult and young marmosets liked to explore the open area, but the young animals showed more interest than adults. Furthermore, when one of the closed compartments was light and the other dark, the adult marmosets showed a preference for the dark compartment, but the young animals had no preference. These results suggest that the exploratory behavior and the light-dark preference in marmosets are age-dependent. Our study provides a new method to study exploration, anxiety, and fear in marmosets. |
| 学科主题 | Neurosciences |
| 收录类别 | SCI |
| 资助信息 | Youth Innovation Promotion Association of the Chinese Academy of Sciences; SA-SIBS scholarship; National Basic Research Development Program (973 Program) of China [2011CBA00400]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDB02020100] |
| 语种 | 英语 |
| 公开日期 | 2014-07-30 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/2606]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Wang, YW,Fang, Q,Gong, N. A modified light-dark box test for the common marmoset[J]. NEUROSCIENCE BULLETIN,2014,30(3):394-400. |
| APA | Wang, YW,Fang, Q,&Gong, N.(2014).A modified light-dark box test for the common marmoset.NEUROSCIENCE BULLETIN,30(3),394-400. |
| MLA | Wang, YW,et al."A modified light-dark box test for the common marmoset".NEUROSCIENCE BULLETIN 30.3(2014):394-400. |
入库方式： OAI收割
来源：上海神经科学研究所
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