Super-resolution endoscopy for real-time wide-field imaging
文献类型：期刊论文
| 作者 | Wang FF(王飞飞); Lai, Hok Sum Sam; Liu LQ(刘连庆) ; Li P(李盼); Yu HB(于海波); Liu Z(刘柱); Wang YC(王越超); Li WJ(李文荣)
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| 刊名 | OPTICS EXPRESS
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| 出版日期 | 2015 |
| 卷号 | 23期号:13页码:16803-16811 |
| ISSN号 | 1094-4087 |
| 产权排序 | 1 |
| 通讯作者 | 李文荣 |
| 中文摘要 | Resolving subcellular structures in vitro beyond optical diffraction barrier by a light microscope has achieved significant development since the advancement of super-resolution fluorescence microscopes, such as stimulated emission depletion (STED) microscopy, stochastic optical reconstruction microscopy (STORM) and photoactivated localization microscopy (PALM). However, the resolution of observation in deep and dense in vivo tissues is still confined to cellular level presently, and hence, exploring image details at subcellular level or even beyond organelle level in vivo has continued to attract much research attention. Currently, endoscopy provides an effective way to achieve in vivo observations and is compatible with mature optical microscopy technologies, but its resolution is usually confined to similar to 1 mu m. Here we report a new endoscopy method by functionalizing graded-index (GRIN) lens with microspheres for real-time white-light or fluorescent super-resolution imaging. The capability of resolving objects with feature size of similar to lambda/5, which breaks the diffraction barrier of traditional GRIN lens based endoscopes by a factor of two, has been demonstrated by using this superresolution endoscopy method. Further development of such a superresolution endoscopy technique may provide new opportunities for in vivo life sciences studies. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Optics |
| 研究领域[WOS] | Optics |
| 关键词[WOS] | FLUORESCENCE MICROENDOSCOPY ; HIGH-SPEED ; MICROSCOPY ; MICROSPHERE ; RESOLUTION ; NANOSCOPE ; BREAKING ; PHOTON ; DEPTH ; LIMIT |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| WOS记录号 | WOS:000358543300032 |
| 源URL | [http://ir.sia.cn/handle/173321/16853]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 推荐引用方式 GB/T 7714 | Wang FF,Lai, Hok Sum Sam,Liu LQ,et al. Super-resolution endoscopy for real-time wide-field imaging[J]. OPTICS EXPRESS,2015,23(13):16803-16811. |
| APA | Wang FF.,Lai, Hok Sum Sam.,Liu LQ.,Li P.,Yu HB.,...&Li WJ.(2015).Super-resolution endoscopy for real-time wide-field imaging.OPTICS EXPRESS,23(13),16803-16811. |
| MLA | Wang FF,et al."Super-resolution endoscopy for real-time wide-field imaging".OPTICS EXPRESS 23.13(2015):16803-16811. |
入库方式： OAI收割
来源：沈阳自动化研究所
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