中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [17]
采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2012 [17]
学科主题
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浏览/检索结果:
共17条,第1-10条
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发表日期:2012
专题:上海药物研究所
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Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 卷号: 696, 期号: 1-3, 页码: 43-53
作者:
Zhu, Hengrui
;
Liu, Zulong
;
Tang, Lisha
;
Liu, Junhua
;
Zhou, Mei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Gypenoside aglycon
Gynostemma pentaphyllum
Multidrug resistance (MDR)
KB/VCR cells
P-glycoprotein (P-gp)
Multidrug resistance associated protein 1 (MRP1)
Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking
期刊论文
OAI收割
JOURNAL OF MOLECULAR MODELING, 2012, 卷号: 18, 期号: 12, 页码: 4995-5003
作者:
Hu, Guoping
;
Li, Xi
;
Sun, Xianqiang
;
Lu, Weiqiang
;
Liu, Guixia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Drug repositioning
HIV-1 Integrase
Human LEDGF/p75 protein
Molecular docking
Protein-protein interaction
Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 23, 页码: 7237-7242
作者:
He, Hai-Bing
;
Gao, Li-Xin
;
Deng, Qi-Feng
;
Ma, Wei-Ping
;
Tang, Chun-Lan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
4,4-Dimethyl lithocholic acids
Protein tyrosine phosphatase 1B
Inhibitor
SAR
Diabetes
Identification of modification sites on human serum albumin and human hemoglobin adducts with houttuynin using liquid chromatography coupled with mass spectrometry
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2012, 卷号: 26, 期号: 11, 页码: 1377-1385
作者:
Deng, Zhipeng
;
Zhong, Dafang
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
houttuynin
human serum albumin
human hemoglobin
LC
MSn
adduct types
modification sites
Development of Cell-Active N-6-Methyladenosine RNA Demethylase FTO Inhibitor
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 卷号: 134, 期号: 43, 页码: 17963-17971
作者:
Chen, Baoen
;
Ye, Fei
;
Yu, Lu
;
Jia, Guifang
;
Huang, Xiaotian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2012, 卷号: 40, 期号: 10, 页码: 2041-2053
作者:
Li, Liang
;
Chen, Xiaoyan
;
Zhou, Jialan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Computational drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 9, 页码: 1131-1140
作者:
Ou-Yang, Si-sheng
;
Lu, Jun-yan
;
Kong, Xiang-qian
;
Liang, Zhong-jie
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
computational drug discovery
target identification
lead discovery
Small-molecule STAT3 Signaling Pathway Modulators from Polygonum cuspidatum
期刊论文
OAI收割
PLANTA MEDICA, 2012, 卷号: 78, 期号: 14, 页码: 1568-1570
作者:
Liu, Jiawei
;
Zhang, Qing
;
Chen, Kaotang
;
Liu, Jingli
;
Kuang, Shan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Polygonum cuspidatum
Polygonaceae
STAT3 signaling
modulators
2-methoxystypandrone
Discovery and Optimization of 1,3,4-Trisubstituted-pyrazolone Derivatives as Novel, Potent, and Nonsteroidal Farnesoid X Receptor (FXR) Selective Antagonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 16, 页码: 7037-7053
作者:
Huang, Huang
;
Yu, Ying
;
Gao, Zhenting
;
Zhang, Yong
;
Li, Chenjing
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Identification of the ortho-Benzoquinone Intermediate of 5-O-Caffeoylquinic Acid In Vitro and In Vivo: Comparison of Bioactivation under Normal and Pathological Situations
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2012, 卷号: 40, 期号: 8, 页码: 1628-1640
作者:
Xie, Cen
;
Zhong, Dafang
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08