中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
南海海洋研究所 [1]
自动化研究所 [1]
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OAI收割 [9]
内容类型
期刊论文 [9]
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2023 [1]
2022 [1]
2021 [1]
2020 [1]
2019 [2]
2018 [1]
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浏览/检索结果:
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内容类型:期刊论文
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Ent- kaurane diterpenoids from Isodon japonica var. glaucocalyx with PCSK9 inhibitory activities
期刊论文
OAI收割
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 57, 页码: 56-61
作者:
Wang, Ge
;
Chen, Tong
;
Guo, Peng-Ju
;
Peng, Shou
;
Wang, Wen-Qiong
  |  
收藏
  |  
浏览/下载:236/0
  |  
提交时间:2023/10/17
Purine-diterpenoid derivatives
Ent -kaurane diterpenoid
PCSK9 inhibition activity
PCSK9 inhibitors for anti-inflammation in atherosclerosis: protocol for a systematic review and meta-analysis of randomised controlled trials
期刊论文
OAI收割
BMJ OPEN, 2022, 卷号: 12, 期号: 11, 页码: 6
作者:
Luo, Jichang
;
Liao, Wanying
;
Wang, Xue
;
Xu, Ran
;
Li, Wei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/03/20
VASCULAR MEDICINE
CLINICAL PHARMACOLOGY
Coronary heart disease
Lipid disorders
Protocols & guidelines
Euphornin L promotes lipid clearance by dual regulation of LDLR and PCSK9
期刊论文
OAI收割
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021, 卷号: 22, 期号: 6, 页码: 9
作者:
Li, Huihui
;
Li, Jun
;
Zhang, Xianjing
;
Li, Jiaomeng
;
Xi, Cong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/06/15
euphornin L
lipid-lowering activity
low density lipoprotein receptor
proprotein convertase subtilisin
kexin type 9
extracellular signal-regulated kinase protein
secretion
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Indole alkaloid from Nauclea latifolia promotes LDL uptake in HepG2 cells by inhibiting PCSK9
期刊论文
OAI收割
Phytomedicine, 2018
作者:
Aggrey, Mike Okweesi
;
Li, Hui-Hui
;
Wang, Wen-Qiong
;
Wang, Yiping
;
Xuan, Li-Jiang
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/03/13
Anti-hyperlipidemia
Nauclea Latifolia
Pcsk9
Sar
Indoloquinolizidine Alkaloids
Two proprotein convertase subtilisin/kexin type 9 (PCSK9) paralogs from the tropical sea cucumber (Stichopus monotuberculatus): Molecular characterization and inducible expression with immune challenge
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2016, 卷号: 56, 页码: 255-262
作者:
Ren, Chunhua
;
Chen, Ting
;
Jiang, Xiao
;
Sun, Hongyan
;
Qian, Jing
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2016/12/22
Proprotein convertase subtilisin/kexin type 9
Stichopus monotuberculatus
cDNA
Gene structure
Innate immune defense
MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 8, 页码: 994-1004
作者:
Yan, Hong
;
Ma, Yan-ling
;
Gui, Yu-zhou
;
Wang, Shu-mei
;
Wang, Xin-bo
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
cholesterol homeostasis
LDLR
MG132
proteasome inhibition
PKC
PCSK9
pravastatin
HepG2
cells