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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [20]
采集方式
OAI收割 [20]
内容类型
期刊论文 [20]
发表日期
2022 [1]
2021 [3]
2020 [1]
2017 [4]
2015 [3]
2014 [2]
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存缴方式:oaiharvest
内容类型:期刊论文
专题:上海药物研究所
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Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation
期刊论文
OAI收割
THERANOSTICS, 2022, 卷号: 12, 期号: 11, 页码: 5220-5236
作者:
Guo, Ren
;
Jia, Xiaohui
;
Ding, Zhenbin
;
Wang, Gang
;
Jiang, Mengmeng
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/08/30
Mixed lineage kinase domain-like protein
MLKL
liver fibrosis
liver parenchymal cells
hepatocyte
hepatic stellate cells
necroptosis
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
OAI收割
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/04
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Xie, Xiao-Yu
;
Pan, You-Lu
;
Li, Gang-Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Pyridazine-3-carboxamides
CB2 agonist
Structure-activity relationships
Molecular docking
logP
Luteolin-7-diglucuronide attenuates isoproterenol-induced myocardial injury and fibrosis in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 331-341
作者:
Ning, Bing-Bing
;
Zhang, Yong
;
Wu, Dan-Dan
;
Cui, Jin-Gang
;
Liu, Li
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
luteolin-7-diglucuronide
ISO
myocardial injury
myocardial fibrosis
NADPH oxidase
collagen genes
microRNAs
TGF beta
Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease
期刊论文
OAI收割
STEM CELL REPORTS, 2017, 卷号: 8, 期号: 1, 页码: 84-94
作者:
Huang, Shichao
;
Mao, Jianxin
;
Ding, Kan
;
Zhou, Yue
;
Zeng, Xianglu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Synthetic Analogues of Betulinic Acid as Potent Inhibitors of PS1/BACE1 Interaction to Reduce A Generation
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 1, 页码: 103-112
作者:
Zhang, Chenlu
;
Wang, Xiaoyin
;
Cui, Jin
;
Li, Xiaohang
;
Zhang, Yangming
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Alzheimer's disease
PS1
BACE1 interaction
A
betulinic acid
SAR
Screening antitumor bioactive fraction from Sauromatum giganteum (Engl.) Cusimano & Hett and sensitive cell lines with the serum pharmacology method and identification by UPLC-TOF-MS
期刊论文
OAI收割
Molecules (Basel, Switzerland), 2015, 卷号: 20, 期号: 3, 页码: 4290-306
作者:
Gao, Shi-Yong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08