中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2019 [7]
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发表日期:2019
专题:上海药物研究所
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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:
Wang, Yulan
;
Dai, Yang
;
Wu, Xiaowei
;
Li, Fei
;
Liu, Bo
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Identification and characterization of potent and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B)
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 16, 页码: 2358-2363
作者:
Jin, Jia
;
Ye, Xiaoqing
;
Boateng, Derrick
;
Dai, Kaili
;
Ye, Fei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
PTP1B
TCPTP
Type 2 diabetes
Selective inhibitors
Dihydropyridine thione
Gold-catalyzed Rapid Construction of Nitrogen-containing Heterocyclic Compound Library with Scaffold Diversity and Molecular Complexity
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2019, 卷号: 361, 期号: 6, 页码: 1419-1440
作者:
Qiao, Jin
;
Jia, Xiuwen
;
Li, Pinyi
;
Liu, Xiaoyan
;
Zhao, Jingwei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Alkynes
Amines
Cascade reaction
Compound library
Gold
Scaffold diversity
Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 30
作者:
Jia, Xiuwen
;
Li, Pinyi
;
Liu, Xiaoyan
;
Lin, Jiafu
;
Chu, Yiwen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
amine nucleophiles
alkynoic acids
cascade reaction
gold catalysis
fused N-heterocycles
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:
Ye, Xiaoqing
;
Zhang, Rukang
;
Lian, Fulin
;
Zhang, Weiyao
;
Lu, Wenchao
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
WDR5-MLL1 interaction
Leukemia
Small-molecule
High-throughput screening
Fluorescence polarization (FP)
Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 22
作者:
Zhao, Fei
;
Li, Pinyi
;
Liu, Xiaoyan
;
Jia, Xiuwen
;
Wang, Jiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
amide bond
sulfonamide bond
alkynes
addition reaction
aminoacylation
aminosulfonylation