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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
采集方式
OAI收割 [18]
内容类型
期刊论文 [18]
发表日期
2022 [1]
2021 [2]
2020 [2]
2019 [1]
2018 [1]
2016 [2]
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共18条,第1-10条
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内容类型:期刊论文
专题:上海药物研究所
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A novel hybrid scan approach enabling the ion-mobility separation and the alternate data-dependent and data-independent acquisitions (HDDIDDA): Its combination with off-line two-dimensional liquid chromatography for comprehensively characterizing the multicomponents from Compound Danshen Dripping Pill
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2022, 卷号: 1193, 页码: 12
作者:
Wang, Hong-da
;
Wang, Hui-min
;
Wang, Xiang-yang
;
Xu, Xiao-yan
;
Hu, Ying
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/08/16
Alternate data-independent and data-dependent acquisition
Ion mobility/quadrupole time-of-flight mass spectrometry
Off-line two-dimensional liquid chromatography
Multicomponent characterization
Compound Danshen dripping pill
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Diffuse large B-cell lymphoma with low F-18-fluorodeoxyglucose avidity features silent B-cell receptor signaling
期刊论文
OAI收割
LEUKEMIA & LYMPHOMA, 2020, 页码: 8
作者:
Sheng, Dong
;
Li, Ting
;
Wang, Wei-Ge
;
Li, Meng-Jiao
;
Jiang, Kai-Long
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Diffuse large B-cell lymphoma
PET
CT
B-cell receptor signaling
pSYK
GLUT1
HK2
Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 602-614
作者:
Dong, Xiao-Wu
;
Zhang, Jian-Kang
;
Xu, Lei
;
Che, Jin-Xin
;
Cheng, Gang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Proteasome inhibitors
Tripeptide
Covalent docking
Interaction mode
Simultaneously targeted and untargeted multicomponent characterization of Erzhi Pill by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry
期刊论文
OAI收割
Journal of Chromatography A, 2018
作者:
Fu, Ling-ling
;
Ding, Hui
;
Han, Li-feng
;
Jia, Li
;
Yang, Wen-zhi
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Novel CHOP activator LGH00168 induces necroptosis in A549 human lung cancer cells via ROS-mediated ER stress and NF-kappa B inhibition
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1381-1390
作者:
Ma, Yi-ming
;
Peng, Yan-min
;
Zhu, Qiong-hua
;
Gao, An-hui
;
Chao, Bo
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
CHOP
LGH00168
ER stress
NF-kappa B
necroptosis
RIP1
ROS
non-small cell lung cancer A549 cells
cancer xenograft mice
Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 81-90
作者:
Gong, Chao-Jun
;
Gao, An-Hui
;
Zhang, Yang-Ming
;
Su, Ming-Bo
;
Chen, Fei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Bisthiazole
Histone deacetylases
ZBG
Trifluoromethyl ketones
Azoxystrobin, a mitochondrial complex III Q(o) site inhibitor, exerts beneficial metabolic effects in vivo and in vitro
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2014, 卷号: 1840, 期号: 7, 页码: 2212-2221
作者:
Gao, An-Hui
;
Fu, Yan-Yun
;
Zhang, Kun-Zhi
;
Zhang, Mei
;
Jiang, Hao-Wen
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Azoxystrobin
Mitochondria complex III
Metabolic diseases
AMP-activated protein kinase